DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11836 and Cela3b

DIOPT Version :9

Sequence 1:	NP_001356925.1	Gene:	CG11836 / 43007	FlyBaseID:	FBgn0039272	Length:	333	Species:	Drosophila melanogaster
Sequence 2:	NP_080695.1	Gene:	Cela3b / 67868	MGIID:	1915118	Length:	269	Species:	Mus musculus

Alignment Length:	260	Identity:	85/260 - (32%)
Similarity:	129/260 - (49%)	Gaps:	27/260 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 CG--FSNEEIRIVGGKPTGVNQYPWMARIVY--DGKFH--CGGSLLTKDYVLSAAHCVKKLRKSK 146
            ||  ..|...|:|.|:....:.:||...:.|  ||.||  |||||:|.|:||:|.||:...|  .
Mouse    17 CGQPSHNPSSRVVNGEEAVPHSWPWQVSLQYEKDGSFHHTCGGSLITPDWVLTAGHCISTSR--T 79

  Fly   147 IRVIFGDHDQEI-TSESQAIQRAVTAVIKHKSFDP--DTYNNDIALLRLRKPISFSKIIKPICLP 208
            .:|:.|:|::.: ..:.|.|......:..|..::.  .:..|||||::|.:.......::..|||
Mouse    80 YQVVLGEHERGVEEGQEQVIPINAGDLFVHPKWNSMCVSCGNDIALVKLSRSAQLGDAVQLACLP 144

  Fly   209 RYNYDPAGRI---GT---VVGWGRTSEGGELPSIVNQVKVPIMSITECRNQRYKSTRITSSMLCA 267
                 |||.|   |.   :.||||.|..|.||..:.|..:|::....|....:....:.::|:||
Mouse   145 -----PAGEILPNGAPCYISGWGRLSTNGPLPDKLQQALLPVVDYEHCSRWNWWGLSVKTTMVCA 204

  Fly   268 GRPSMDSCQGDSGGPL--LLSNGVKYFIVGIVSW--GVGCGREGYPGVYSRVSKFIPWIKSNLEN 328
            |......|.|||||||  ...||. :.:.|:.|:  .:||.....|.|::|||.||.||:..:.|
Mouse   205 GGDIQSGCNGDSGGPLNCPADNGT-WQVHGVTSFVSSLGCNTLRKPTVFTRVSAFIDWIEETIAN 268

Fly 329 328
Mouse 269 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11836	NP_001356925.1	Tryp_SPc	97..325	CDD:238113	80/244 (33%)
Cela3b	NP_080695.1	Tryp_SPc	27..262	CDD:214473	79/242 (33%)
Cela3b	NP_080695.1	Tryp_SPc	28..265	CDD:238113	80/244 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5507
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.860