DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11836 and st14a

DIOPT Version :9

Sequence 1:	NP_001356925.1	Gene:	CG11836 / 43007	FlyBaseID:	FBgn0039272	Length:	333	Species:	Drosophila melanogaster
Sequence 2:	NP_001035441.2	Gene:	st14a / 678603	ZFINID:	ZDB-GENE-030131-6496	Length:	834	Species:	Danio rerio

Alignment Length:	266	Identity:	104/266 - (39%)
Similarity:	156/266 - (58%)	Gaps:	17/266 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 DTEDEVEYTENSSLKNCDCDCGFSNEEIRIVGGKPTGVNQYPWMARIVYDGKFH-CGGSLLTKDY 131
            |.:|:.  .:||...||:|... :.::.|||||:.....::||...:......| ||||::.:.:
Zfish   571 DGQDDC--GDNSDESNCNCGTK-AYKKSRIVGGQDAFEGEFPWQVSLHIKNIAHVCGGSIINERW 632

  Fly   132 VLSAAHCVK---KLRKSK---IRVIFGDHDQEITSESQAIQRAVTAVIKHKSFDPDTYNNDIALL 190
            :::|||||:   |::.|:   ..|..|.|.|:  .:..|.:|.:..||.|..::..||:|||||:
Zfish   633 IVTAAHCVQDDVKIKYSQPGTWEVFLGLHSQK--DKLTATKRLLKQVIPHPYYNAYTYDNDIALM 695

  Fly   191 RLRKPISFSKIIKPICLP-RYNYDPAGRIGTVVGWGRTSEGGELPSIVNQVKVPIMSITECRNQR 254
            .:..|::||..|:|:||| ..:..|||....:.|||.|.|||...:::.:.:|.|::.|.| ||
Zfish   696 EMESPVTFSDTIRPVCLPTATDTFPAGTSVFISGWGATREGGSGATVLQKAEVRIINSTVC-NQ- 758

  Fly   255 YKSTRITSSMLCAGRPS--MDSCQGDSGGPLLLSNGVKYFIVGIVSWGVGCGREGYPGVYSRVSK 317
            ....:|||.|.|||..|  :|:|||||||||...:|.:.|:.|:||||.||.|...||:||.|.|
Zfish   759 LMGGQITSRMTCAGVLSGGVDACQGDSGGPLSFPSGKRMFLAGVVSWGDGCARRNKPGIYSNVPK 823

  Fly   318 FIPWIK 323
            |..|||
Zfish   824 FRAWIK 829

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11836	NP_001356925.1	Tryp_SPc	97..325	CDD:238113	96/237 (41%)
st14a	NP_001035441.2	SEA	77..168	CDD:279699
		CUB	219..322	CDD:238001
		CUB	329..431	CDD:238001
		LDLa	443..472	CDD:238060
		LDLa	474..508	CDD:238060
		LDLa	510..544	CDD:238060
		LDLa	550..585	CDD:238060	4/15 (27%)
		Tryp_SPc	596..828	CDD:214473	94/235 (40%)
		Tryp_SPc	597..831	CDD:238113	96/237 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820