DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11836 and PRSS22

DIOPT Version :9

Sequence 1:	NP_001356925.1	Gene:	CG11836 / 43007	FlyBaseID:	FBgn0039272	Length:	333	Species:	Drosophila melanogaster
Sequence 2:	NP_071402.1	Gene:	PRSS22 / 64063	HGNCID:	14368	Length:	317	Species:	Homo sapiens

Alignment Length:	263	Identity:	86/263 - (32%)
Similarity:	129/263 - (49%)	Gaps:	28/263 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 CGFSNEEIRIVGGKPTGVNQYPWMARIVYDGKFHCGGSLLTKDYVLSAAHCVK-KLRKSKIRVIF 151
            ||...:..|:|||:.:..:::||:..|..:|..||.|||||..:|::||||.| .|.|..:..:.
Human    41 CGKPQQLNRVVGGEDSTDSEWPWIVSIQKNGTHHCAGSLLTSRWVITAAHCFKDNLNKPYLFSVL 105

  Fly   152 ---------GDHDQEITSESQAIQRAVTAVIKHKSFD-PDTYNNDIALLRLRKPISFSKIIKPIC 206
                     |...|::         .|..|..|..:. .:....||||:||.:.|.||:.:.|||
Human   106 LGAWQLGNPGSRSQKV---------GVAWVEPHPVYSWKEGACADIALVRLERSIQFSERVLPIC 161

  Fly   207 LPRYN-YDPAGRIGTVVGWGRTSEGGEL--PSIVNQVKVPIMSITECRNQRYKST---RITSSML 265
            ||..: :.|......:.|||...:|..|  |..:.::||||:....|.:..::..   .||..||
Human   162 LPDASIHLPPNTHCWISGWGSIQDGVPLPHPQTLQKLKVPIIDSEVCSHLYWRGAGQGPITEDML 226

  Fly   266 CAG--RPSMDSCQGDSGGPLLLSNGVKYFIVGIVSWGVGCGREGYPGVYSRVSKFIPWIKSNLEN 328
            |||  ....|:|.|||||||:......:.:.||:|||.||.....||||..:|....|::..::.
Human   227 CAGYLEGERDACLGDSGGPLMCQVDGAWLLAGIISWGEGCAERNRPGVYISLSAHRSWVEKIVQG 291

  Fly   329 TCL 331
            ..|
Human   292 VQL 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11836	NP_001356925.1	Tryp_SPc	97..325	CDD:238113	82/246 (33%)
PRSS22	NP_071402.1	Tryp_SPc	50..288	CDD:238113	82/246 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910