DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11836 and tmprss13b

DIOPT Version :9

Sequence 1:	NP_001356925.1	Gene:	CG11836 / 43007	FlyBaseID:	FBgn0039272	Length:	333	Species:	Drosophila melanogaster
Sequence 2:	XP_005165399.1	Gene:	tmprss13b / 564693	ZFINID:	ZDB-GENE-090309-2	Length:	475	Species:	Danio rerio

Alignment Length:	319	Identity:	110/319 - (34%)
Similarity:	162/319 - (50%)	Gaps:	43/319 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 GFNESDAINTIHTGHNKRTSKFLFDTIFRISSGVSNAFGLSDTEDEVEYTENSSLKNCDCDCGFS 91
            ||.:|.:...:      :::..:|.::  .|..|:|..|..:|.......::.||: | ||||..
Zfish   178 GFRQSYSYGVV------KSNSPMFQSV--NSQLVNNIQGRVNTSSSCPDQQSVSLQ-C-CDCGRP 232

  Fly    92 NEEIRIVGGKPTGVNQYPWMARIVYDGKFHCGGSLLTKDYVLSAAHCVKKLRK-----SKIRVIF 151
            ....||:||.......:||.|.:.:.||..|||||:..|::::||||..|...     |..:|..
Zfish   233 PVSSRIIGGSVAAEGHWPWQASLHFQGKHSCGGSLVAPDFIITAAHCFPKETSGSQLPSNWKVYI 297

  Fly   152 GDHDQ-EITSESQAIQRAVTAVIKHKSFDPDTYNNDIALLRLRKPISFSKIIKPICLP--RYNYD 213
            |...| ::.|...     |..:|.|:.::|.|.|.|||||:|.||.|   .::|||||  ...:.
Zfish   298 GFVSQLKLPSPYY-----VKEIILHEKYNPTTKNYDIALLKLNKPAS---DVEPICLPVIGQTFP 354

  Fly   214 PAGRIGTVVGWGRTSEGGELPSIVNQVKVPIMSIT-------ECRNQRYKSTRITSSMLCAG--R 269
            ||.:..| .|:|...:|.      |.|...:|.:|       .|.:....:..||.:|.|||  |
Zfish   355 PAKQCWT-TGFGVIRQGS------NSVSTSLMEVTVSLIDSSVCNSPNVYNGEITENMQCAGDLR 412

  Fly   270 PSMDSCQGDSGGPLLL-SNGVKYFIVGIVSWGVGCGREGYPGVYSRVSKFIPWIKSNLE 327
            ...|||||||||||.. ||..::|:.|:.|||.|||:...|||||.|:|::.||.|.::
Zfish   413 GGKDSCQGDSGGPLACKSNDGQWFLTGVTSWGEGCGQVNRPGVYSDVAKYLMWIYSKMQ 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11836	NP_001356925.1	Tryp_SPc	97..325	CDD:238113	92/245 (38%)
tmprss13b	XP_005165399.1	SRCR_2	147..230	CDD:295335	14/61 (23%)
		Tryp_SPc	237..466	CDD:214473	91/243 (37%)
		Tryp_SPc	238..469	CDD:238113	92/245 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	180	1.000	Domainoid score	I3447
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6379
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.910