DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11836 and masp2

DIOPT Version :9

Sequence 1:	NP_001356925.1	Gene:	CG11836 / 43007	FlyBaseID:	FBgn0039272	Length:	333	Species:	Drosophila melanogaster
Sequence 2:	NP_001116330.1	Gene:	masp2 / 560277	ZFINID:	ZDB-GENE-060130-154	Length:	684	Species:	Danio rerio

Alignment Length:	262	Identity:	89/262 - (33%)
Similarity:	136/262 - (51%)	Gaps:	36/262 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 CGFSNEEI-RIVGGKPTGVNQYPWMARIVYDGKFHCGGSLLTKDYVLSAAHCVKKLRKS-KIRVI 150
            ||....:: :::||:....|:.||...|....||..|.|||:..:||:|||.||....| .:::.
Zfish   426 CGQPELKLSKVIGGENAEKNEIPWQVMIRMGTKFIGGASLLSDGWVLTAAHVVKSFEDSANLQLR 490

  Fly   151 FG---DHDQEITSESQAIQRAVTAVIKHKSFDPD--TYNNDIALLRLRKPISFSKIIKPICLP-- 208
            .|   .||.|      |:......:..|..:..|  .:|:||||::|...:..||.:.|:|||
Zfish   491 MGTVKHHDNE------AVVGIPQKIFIHPQYHHDNVNFNHDIALIKLEYKVPVSKAVMPVCLPGR 549

  Fly   209 --RYNYDPAGRIGTVVGWGRTSEGGELPSI----VNQVKVPIMSITECRNQRYKST-------RI 260
              |:.. .|..:|.|.|||.::.  ..|::    :..|.:|:.:..:|:. :|.||       .:
Zfish   550 EERFVL-KANDVGKVSGWGVSNI--NTPALFSGNLKYVHLPVSNFNDCKT-KYDSTVTSKGKLVV 610

  Fly   261 TSSMLCAG--RPSMDSCQGDSGGPLLL--SNGVKYFIVGIVSWGVGCGREGYPGVYSRVSKFIPW 321
            |.:|:|||  :...||||||||||...  .....:||.||||||.||.:.||.|||::||.::.|
Zfish   611 TENMICAGFSQGGKDSCQGDSGGPFAFFDKQSKSWFIGGIVSWGHGCAQAGYYGVYTKVSNYLSW 675

  Fly   322 IK 323
            |:
Zfish   676 IE 677

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11836	NP_001356925.1	Tryp_SPc	97..325	CDD:238113	87/252 (35%)
masp2	NP_001116330.1	CUB	24..130	CDD:214483
		EGF_CA	134..176	CDD:214542
		CUB	180..289	CDD:278839
		CCP	296..357	CDD:214478
		CCP	362..410	CDD:153056
		Tryp_SPc	435..676	CDD:214473	85/250 (34%)
		Tryp_SPc	436..679	CDD:238113	87/252 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910