DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11836 and tmprss13a

DIOPT Version :9

Sequence 1:	NP_001356925.1	Gene:	CG11836 / 43007	FlyBaseID:	FBgn0039272	Length:	333	Species:	Drosophila melanogaster
Sequence 2:	NP_001152984.1	Gene:	tmprss13a / 559754	ZFINID:	ZDB-GENE-090309-3	Length:	506	Species:	Danio rerio

Alignment Length:	312	Identity:	107/312 - (34%)
Similarity:	175/312 - (56%)	Gaps:	29/312 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 GFN---ESDAINTIHTGH--NKRTSKFLFDTIFRISSGVSNAFGLSDTEDEVEYTENSSLKNCDC 86
            ||.   ||.|:|:..:..  .:.||..|...:..:|||.     |.|        ::.||: |.
Zfish   209 GFRRSYESSALNSKSSEALILEPTSGLLIQGLANVSSGC-----LDD--------KSVSLQ-CS- 258

  Fly    87 DCGFSNEEIRIVGGKPTGVNQYPWMARIVYDGKFHCGGSLLTKDYVLSAAHCVK-KLRKSKIRVI 150
            |||......||:||..:.:.||||...:.|:....|||:|::.|:::|||||.: |:..|...::
Zfish   259 DCGKQQSSSRIIGGTTSELGQYPWQVSLHYNKAHVCGGTLISPDFIVSAAHCFQGKMANSAYWLV 323

  Fly   151 FGDHDQEITSESQAIQRAVTAVIKHKSFDPDTYNNDIALLRLRKPISFSKIIKPICLPRYNYDPA 215
            :..   .::.:|..:...|..:|..:.::.||.:||:|||.|.:|::||...:|:|||.:|...:
Zfish   324 YVG---IVSQQSLGMPYLVKKIIVSEKYNSDTNDNDVALLILSRPVAFSYTTQPVCLPTFNQTFS 385

  Fly   216 GRIGT-VVGWGRTSEGGE-LPSIVNQVKVPIMSITECRNQRYKSTRITSSMLCAG--RPSMDSCQ 276
            |.:.. ..|:|.|.:|.: ..|.:..|.|.|:..:.|.:.:.....||::|:|||  :...||||
Zfish   386 GGLQCWTSGFGTTKQGADRASSSLMSVSVNIIDSSVCNSCQIYCGLITNNMICAGDLKGGRDSCQ 450

  Fly   277 GDSGGPLLL-SNGVKYFIVGIVSWGVGCGREGYPGVYSRVSKFIPWIKSNLE 327
            |||||||:. .:..::::|||.|||.|||::..|||||||:.|:|||.:.::
Zfish   451 GDSGGPLVCKDDNNRWYLVGITSWGAGCGQKQKPGVYSRVTSFLPWIYTKMQ 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11836	NP_001356925.1	Tryp_SPc	97..325	CDD:238113	86/233 (37%)
tmprss13a	NP_001152984.1	SRCR_2	178..261	CDD:295335	18/66 (27%)
		Tryp_SPc	268..497	CDD:214473	85/231 (37%)
		Tryp_SPc	269..497	CDD:238113	84/230 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	180	1.000	Domainoid score	I3447
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6379
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.910