Protein Alignment CG11836 and PLAT

DIOPT Version :10

• Sequence 1: NP_001356925.1
• Gene: CG11836 / 43007
• FlyBaseID: FBgn0039272
• Length: 333
• Species: Drosophila melanogaster
• Sequence 2: NP_000921.1
• Gene: PLAT / 5327
• HGNCID: 9051
• Length: 562
• Species: Homo sapiens
• Alignment Length: 333
• Identity: 101/333 - (30%)
• Similarity: 156/333 - (46%)
• Gaps: 65/333 - (19%)

  Fly    46 SKFLFDTIFRISSGVSNAFGLSDTEDEVEYTENSS---------LKN-------CD---CD-CG- 89
            |..|...::...:..:.|.||.    :..|..|..         |||       ||   |. ||
Human   241 SMILIGKVYTAQNPSAQALGLG----KHNYCRNPDGDAKPWCHVLKNRRLTWEYCDVPSCSTCGL 301

  Fly    90 --FSNEEIRIVGGKPTGVNQYPWMARIVY------DGKFHCGGSLLTKDYVLSAAHCVKK----- 141
              :|..:.||.||....:..:||.|.|..      ..:|.|||.|::..::||||||.::
Human   302 RQYSQPQFRIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQERFPPH 366

  Fly   142 ----LRKSKIRVIFGDHDQEITSESQAIQRAVTAVIKHKSFDPDTYNNDIALLRLRKPIS----F 198
                :.....||:.|:.:|:...|.         .|.||.||.|||:||||||:|:...|    .
Human   367 HLTVILGRTYRVVPGEEEQKFEVEK---------YIVHKEFDDDTYDNDIALLQLKSDSSRCAQE 422

  Fly   199 SKIIKPICLPRYNYD-PAGRIGTVVGWGRTSEGGELPS-IVNQVKVPIMSITECRNQRYKSTRIT 261
            |.:::.:|||..:.. |......:.|:|:........| .:.:..|.:...:.|.:|...:..:|
Human   423 SSVVRTVCLPPADLQLPDWTECELSGYGKHEALSPFYSERLKEAHVRLYPSSRCTSQHLLNRTVT 487

  Fly   262 SSMLCAGRPSM--------DSCQGDSGGPLLLSNGVKYFIVGIVSWGVGCGREGYPGVYSRVSKF 318
            .:|||||....        |:|||||||||:..|..:..:|||:|||:|||::..||||::|:.:
Human   488 DNMLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMTLVGIISWGLGCGQKDVPGVYTKVTNY 552

  Fly   319 IPWIKSNL 326
            :.||:.|:
Human   553 LDWIRDNM 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11836	NP_001356925.1	Tryp_SPc	97..325	CDD:238113	83/256 (32%)
PLAT	NP_000921.1	FN1	41..83	CDD:214494
		Important for binding to annexin A2	42..52
		EGF	86..117	CDD:394967
		KR	125..209	CDD:238056
		Kringle	215..296	CDD:395005	12/58 (21%)
		Tryp_SPc	313..559	CDD:238113	82/254 (32%)