DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11836 and Prss53

DIOPT Version :9

Sequence 1:	NP_001356925.1	Gene:	CG11836 / 43007	FlyBaseID:	FBgn0039272	Length:	333	Species:	Drosophila melanogaster
Sequence 2:	XP_006230384.1	Gene:	Prss53 / 499270	RGDID:	1566127	Length:	591	Species:	Rattus norvegicus

Alignment Length:	264	Identity:	76/264 - (28%)
Similarity:	123/264 - (46%)	Gaps:	42/264 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 ENSSLKNCDCDCGFSNEEIRIVGGKPTG-VNQYPWMARIVYDGKFHCGGSLLTKDYVLSAAHC-V 139
            |||.:.     ||..:.     ||...| ::|:||.||:.:.||..|||:|:::..||:|||| :
  Rat   329 ENSCVA-----CGSLSS-----GGPQAGALSQWPWDARLKHHGKLACGGALVSEVVVLTAAHCFI 383

  Fly   140 KKLRKSKIRVIFGDHDQEITSESQAIQRAVTAVIKHKSFDPDTYNNDIALLRLRKPISFSKIIKP 204
            .:....:..|..|...:|         ..:..:|.|.::......:|:|.|.|.:|::....::|
  Rat   384 GRQTLEEWSVGLGAGPEE---------WGLKQLILHGAYTHPEGGHDVAFLLLAQPVTLGPGLRP 439

  Fly   205 ICLPRYNYD-PAGRIGTVVGWGRTSEGGELPSIVNQ---VKVPIMSITECRNQRYKS----TRIT 261
            :|||..::. |.|..|.|:  |.|.|.|     :|.   |.|.::....|..|...|    ..|.
  Rat   440 LCLPYADHRLPDGEHGWVL--GLTREAG-----INHPHTVPVTVLGPMACSRQHAASGSTGVPIL 497

  Fly   262 SSMLC---AGRPSMDSCQGDSGGPLLLSNGVKYFIVGIVSWGVGCGREGYPGVYSRVSKFIPWIK 323
            ..|:|   .|.|  ..|:|.||.||:......:|:.|:.|:|..|.....|.|::.:|.:..|:
  Rat   498 PGMICTTVVGEP--PHCEGLSGAPLVHEIRGTWFLAGLHSFGDTCQGSAKPAVFAALSAYEDWV- 559

  Fly   324 SNLE 327
            |||:
  Rat   560 SNLD 563

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11836	NP_001356925.1	Tryp_SPc	97..325	CDD:238113	68/240 (28%)
Prss53	XP_006230384.1	Tryp_SPc	45..310	CDD:238113
Prss53	XP_006230384.1	Tryp_SPc	341..561	CDD:238113	68/238 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920