Protein Alignment CG11836 and KLK12

DIOPT Version :10

• Sequence 1: NP_001356925.1
• Gene: CG11836 / 43007
• FlyBaseID: FBgn0039272
• Length: 333
• Species: Drosophila melanogaster
• Sequence 2: NP_062544.1
• Gene: KLK12 / 43849
• HGNCID: 6360
• Length: 254
• Species: Homo sapiens
• Alignment Length: 244
• Identity: 85/244 - (34%)
• Similarity: 119/244 - (48%)
• Gaps: 33/244 - (13%)

  Fly    86 CDCGFSNEEI-RIVGGKPTGVNQYPWMARIVYDGKFHCGGSLLTKDYVLSAAHCVKKLRKSKIRV 149
            |..|.|.... :|..|...|.|..||...:.......|||.|:...:||:||||    ..|:..|
Human    10 CVLGLSQAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAHC----SGSRYWV 70

  Fly   150 IFGDHDQEITSESQAIQRAVTAVIKHKSFD---------PDTYNNDIALLRLRKPISFSKIIKPI 205
            ..|:|...        |...|..|:|..|.         ..::.:|:.|||||.|:..:..::|:
Human    71 RLGEHSLS--------QLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLRLPVRVTSSVQPL 127

  Fly   206 CLPRYNYDPAGRIGTVVGWGRTSE-GGELPSIVNQVKVPIMSITECRNQRYKSTRITSSMLCAGR 269
            .||. :...||....|.|||.|:. ....|.::..:.:.|:|...|... |.. ||||:|:|||.
Human   128 PLPN-DCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGV-YPG-RITSNMVCAGG 189

  Fly   270 -PSMDSCQGDSGGPLLLSNGVKYFIVGIVSWG-VG-CGREGYPGVYSRV 315
             |..|:|||||||| |:..||   :.|:|||| || ||::|.||||:.:
Human   190 VPGQDACQGDSGGP-LVCGGV---LQGLVSWGSVGPCGQDGIPGVYTYI 234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11836	NP_001356925.1	Tryp_SPc	97..325	CDD:238113	82/232 (35%)
KLK12	NP_062544.1	Tryp_SPc	22..236	CDD:238113	82/232 (35%)