DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11836 and Tmprss11c

DIOPT Version :9

Sequence 1:	NP_001356925.1	Gene:	CG11836 / 43007	FlyBaseID:	FBgn0039272	Length:	333	Species:	Drosophila melanogaster
Sequence 2:	NP_001025468.1	Gene:	Tmprss11c / 435845	MGIID:	3521861	Length:	431	Species:	Mus musculus

Alignment Length:	377	Identity:	105/377 - (27%)
Similarity:	171/377 - (45%)	Gaps:	64/377 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SLKYIIFFWMLTANYSSVLSLEYS---------------KGFNESDAINTIHTGH----NKRTSK 47
            |..|.:.|.:...:|.|..:..||               :.|:||.........|    :|...|
Mouse    61 SFYYHVSFKVNNIDYDSKFAKPYSQEYMDLNKRIVSLMNETFHESKLRKQYVKAHTVQVSKAKGK 125

  Fly    48 FLFDTIFRISSGVSNAFGLSDTEDEVEYT-------------ENSSLKNCD------------CD 87
            .:...:.:..:...|  .:....:.||.|             ::||.|..|            |
Mouse   126 VVIHAVLKFKACYRN--NVEKYWESVETTLYQKLKGQTGLLIDSSSFKFSDIAMPIAEDLLNTC- 187

  Fly    88 CG---FSNEEIRIVGGKPTGVNQYPWMARIVYDGKFHCGGSLLTKDYVLSAAHC-VKKLRKSKIR 148
            ||   ..:...::.||:.....::||.|.:..:....||.:|::..::::|||| ::.......:
Mouse   188 CGRRTIIHRGHKVAGGQDAEEGEWPWQASLQQNSVHRCGATLISNYWLITAAHCFIRAANPKDWK 252

  Fly   149 VIFGDHDQEITSESQAIQRAVTAVIKHKSFDPDTYNNDIALLRLRKPISFSKIIKPICLPR--YN 211
            |.||    .:.|:.|| .|||..:|.|:::....::||||::||..|:.:...|:..|||.  ..
Mouse   253 VSFG----FLLSKPQA-PRAVKNIIIHENYSYPAHDNDIAVVRLSSPVLYESNIRRACLPEATQK 312

  Fly   212 YDPAGRIGTVVGWGRTSEGGELPSIVNQVKVPIMSITECRNQRYKSTRITSSMLCAG--RPSMDS 274
            :.|...: .|.|||.....|:.|:|:.:.||.|:....|.:.:.....||..|:|||  :..:|:
Mouse   313 FPPNSDV-VVTGWGTLKSDGDSPNILQKGKVKIIDNKTCNSGKAYGGMITPGMMCAGFLKGRVDA 376

  Fly   275 CQGDSGGPLLL--SNGVKYFIVGIVSWGVGCGREGYPGVYSRVSKFIPWIKS 324
            |||||||||:.  |.|: :|:.||||||..|.....||||:||:.:..||.|
Mouse   377 CQGDSGGPLVSEDSKGI-WFLAGIVSWGDECALPNKPGVYTRVTYYRDWITS 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11836	NP_001356925.1	Tryp_SPc	97..325	CDD:238113	81/235 (34%)
Tmprss11c	NP_001025468.1	SEA	62..157	CDD:279699	16/96 (17%)
		Tryp_SPc	199..425	CDD:214473	78/232 (34%)
		Tryp_SPc	200..428	CDD:238113	81/235 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	179	1.000	Inparanoid score	I3995
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.960