Protein Alignment CG11836 and KLKB1

DIOPT Version :10

• Sequence 1: NP_001356925.1
• Gene: CG11836 / 43007
• FlyBaseID: FBgn0039272
• Length: 333
• Species: Drosophila melanogaster
• Sequence 2: XP_011530232.1
• Gene: KLKB1 / 3818
• HGNCID: 6371
• Length: 649
• Species: Homo sapiens
• Alignment Length: 292
• Identity: 98/292 - (33%)
• Similarity: 157/292 - (53%)
• Gaps: 42/292 - (14%)

  Fly    55 RISSGVSNAFG----LSDTEDEVEYTENSSLKNCDCDCGFSNEEIRIVGGKPTGVNQYPWMA--R 113
            ||:.|...:.|    |.:|.|....|..:|              .|||||..:...::||..  :
Human   370 RIAYGTQGSSGYSLRLCNTGDNSVCTTKTS--------------TRIVGGTNSSWGEWPWQVSLQ 420

  Fly   114 IVYDGKFH-CGGSLLTKDYVLSAAHCVKKLRKSKIRVIFGD--HDQEITSESQAIQRAVTAVIKH 175
            :....:.| |||||:...:||:||||...|....:..|:..  :..:||.::...|  :..:|.|
Human   421 VKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDTPFSQ--IKEIIIH 483

  Fly   176 KSFDPDTYNNDIALLRLRKPISFSKIIKPICLPRYNYDPAGRIGT------VVGWGRTSEGGELP 234
            :::.....|:||||::|:.|:::::..||||||     ..|...|      |.|||.:.|.||:.
Human   484 QNYKVSEGNHDIALIKLQAPLNYTEFQKPICLP-----SKGDTSTIYTNCWVTGWGFSKEKGEIQ 543

  Fly   235 SIVNQVKVPIMSITECRNQRYKSTRITSSMLCAG--RPSMDSCQGDSGGPLLLSNGVKYFIVGIV 297
            :|:.:|.:|:::..||: :||:..:||..|:|||  ....|:|:|||||||:..:...:.:|||.
Human   544 NILQKVNIPLVTNEECQ-KRYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGIT 607

  Fly   298 SWGVGCGREGYPGVYSRVSKFIPWIKSNLENT 329
            |||.||.|...||||::|::::.||   ||.|
Human   608 SWGEGCARREQPGVYTKVAEYMDWI---LEKT 636

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11836	NP_001356925.1	Tryp_SPc	97..325	CDD:238113	85/240 (35%)
KLKB1	XP_011530232.1	APPLE	21..104	CDD:128519
		APPLE	111..194	CDD:128519
		APPLE	212..295	CDD:128519
		APPLE	303..386	CDD:128519	4/15 (27%)
		Tryp_SPc	402..632	CDD:238113	83/237 (35%)