Protein Alignment CG11836 and TMPRSS9

DIOPT Version :10

• Sequence 1: NP_001356925.1
• Gene: CG11836 / 43007
• FlyBaseID: FBgn0039272
• Length: 333
• Species: Drosophila melanogaster
• Sequence 2: NP_001382442.1
• Gene: TMPRSS9 / 360200
• HGNCID: 30079
• Length: 1093
• Species: Homo sapiens
• Alignment Length: 289
• Identity: 97/289 - (33%)
• Similarity: 149/289 - (51%)
• Gaps: 36/289 - (12%)

  Fly    56 ISSGVSNAFGLSDTEDEVEYTENSSLKNCDCDCGFSNEEI-RIVGGKPTGVNQYPWMARIVYDGK 119
            :|:..:.|.|.:...|..|.|.::.|.    |||.:...: |||||...|..::||...:....:
Human   823 LSAVSTTARGQTPFPDAPEATTHTQLP----DCGLAPAALTRIVGGSAAGRGEWPWQVSLWLRRR 883

  Fly   120 FH-CGGSLLTKDYVLSAAHCVKKLRKSKIRVIFGDHDQ-------EITSESQAIQRAVTAVIKHK 176
            .| ||..|:.:.::||||||..         ::||..|       ...|.::.....|..:.||.
Human   884 EHRCGAVLVAERWLLSAAHCFD---------VYGDPKQWAAFLGTPFLSGAEGQLERVARIYKHP 939

  Fly   177 SFDPDTYNNDIALLRLRKPISFSKIIKPICLPRYNYDPAGR--IGT---VVGWGRTSEGGELPSI 236
            .::..|.:.|:|||.|..|:..|::::|||||    :||.|  .||   :.|||...|||.:...
Human   940 FYNLYTLDYDVALLELAGPVRRSRLVRPICLP----EPAPRPPDGTRCVITGWGSVREGGSMARQ 1000

  Fly   237 VNQVKVPIMSITECRNQRYKSTRITSSMLCAGRP--SMDSCQGDSGGPLLLSN-GVKYFIVGIVS 298
            :.:..|.::|...||  |:...:|:|.|||||.|  .:|||.||:||||.... ..::.:.|:.|
Human  1001 LQKAAVRLLSEQTCR--RFYPVQISSRMLCAGFPQGGVDSCSGDAGGPLACREPSGRWVLTGVTS 1063

  Fly   299 WGVGCGREGYPGVYSRVSKFIPWIKSNLE 327
            ||.||||..:||||:||:....||..:::
Human  1064 WGYGCGRPHFPGVYTRVAAVRGWIGQHIQ 1092

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11836	NP_001356925.1	Tryp_SPc	97..325	CDD:238113	86/243 (35%)
TMPRSS9	NP_001382442.1	SEA	66..>127	CDD:460188
		LDLa	188..223	CDD:238060
		Tryp_SPc	236..465	CDD:214473
		Tryp_SPc	538..768	CDD:238113
		Pneumo_att_G	<717..>867	CDD:114270	15/47 (32%)
		Tryp_SPc	861..1087	CDD:238113	84/240 (35%)