DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11836 and TMPRSS7

DIOPT Version :9

Sequence 1:	NP_001356925.1	Gene:	CG11836 / 43007	FlyBaseID:	FBgn0039272	Length:	333	Species:	Drosophila melanogaster
Sequence 2:	NP_001382436.1	Gene:	TMPRSS7 / 344805	HGNCID:	30846	Length:	843	Species:	Homo sapiens

Alignment Length:	312	Identity:	108/312 - (34%)
Similarity:	159/312 - (50%)	Gaps:	39/312 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 GFNESDAINTIHTGHNKRTSKFLFDTIFRISSGVSNAFGLSDTEDEVEYTENSSLKNCDCDCGFS 91
            |.:|.:...:|..  |.||.|...|..||..:        :..:..|:..:.|..:.|.|... |
Human   547 GRDEQNCTQSIPC--NNRTFKCGNDICFRKQN--------AKCDGTVDCPDGSDEEGCTCSRS-S 600

  Fly    92 NEEIRIVGGKPTGVNQYPWMARIVYDGKFHCGGSLLTKDYVLSAAHCVKKLRKSKIRVIFGDHDQ 156
            :...||:||..|....:||...:.:.|..:||.|:::::::||||||....|.|...........
Human   601 SALHRIIGGTDTLEGGWPWQVSLHFVGSAYCGASVISREWLLSAAHCFHGNRLSDPTPWTAHLGM 665

  Fly   157 EITSESQAIQRAVTAVIKHKSFDPDTYNNDIALLRL--RKPISFSKIIKPICLPRYNYDPAG--- 216
            .:...::.:. .|..::.|:.::..|::.|||||:|  ..|.:..::|:|||:|     |.|
Human   666 YVQGNAKFVS-PVRRIVVHEYYNSQTFDYDIALLQLSIAWPETLKQLIQPICIP-----PTGQRV 724

  Fly   217 RIGT---VVGWGRTSEGGELPSIV-NQVKVPIMSITECRNQRYKSTR--ITSSMLCAGRPS--MD 273
            |.|.   |.||||..|.....|:| .|.:|.::..|.|     .||.  |||.|||||..|  .|
Human   725 RSGEKCWVTGWGRRHEADNKGSLVLQQAEVELIDQTLC-----VSTYGIITSRMLCAGIMSGKRD 784

  Fly   274 SCQGDSGGPLLL---SNGVKYFIVGIVSWGVGCGREGYPGVYSRVSKFIPWI 322
            :|:|||||||..   |:| |:.:.||||||.|.||..:||||:|||.|:|||
Human   785 ACKGDSGGPLSCRRKSDG-KWILTGIVSWGHGSGRPNFPGVYTRVSNFVPWI 835

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11836	NP_001356925.1	Tryp_SPc	97..325	CDD:238113	92/242 (38%)
TMPRSS7	NP_001382436.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	27..67
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.920