DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11836 and prss60.3

DIOPT Version :9

Sequence 1:	NP_001356925.1	Gene:	CG11836 / 43007	FlyBaseID:	FBgn0039272	Length:	333	Species:	Drosophila melanogaster
Sequence 2:	XP_002662541.2	Gene:	prss60.3 / 335152	ZFINID:	ZDB-GENE-030131-7092	Length:	330	Species:	Danio rerio

Alignment Length:	251	Identity:	90/251 - (35%)
Similarity:	138/251 - (54%)	Gaps:	19/251 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 CGFSNEEIRIVGGKPTGVNQYPWMARI---VYDGKFHCGGSLLTKDYVLSAAHCVKKLRKSKIRV 149
            ||.:....|||||.......:||...:   .|.|.| |||||::.::||:||||:..:.::.:.|
Zfish    27 CGQAPLNTRIVGGVNASPGSWPWQVSLHSPKYGGHF-CGGSLISSEWVLTAAHCLSGVSETTLVV 90

  Fly   150 IFGDHDQE---ITSESQAIQRAVTAVIKHKSFDPDTYNNDIALLRLRKPISFSKIIKPICLPRYN 211
            ..|...|:   |...|:.:.::..    |.|::.:|.:||||||||...::|:..|:|:||...|
Zfish    91 YLGRRTQQGINIYETSRNVAKSFV----HSSYNSNTNDNDIALLRLSSAVTFTNYIRPVCLAAQN 151

  Fly   212 --YDPAGRIGTVVGWGRTSEGGELPS--IVNQVKVPIMSITECRNQRYKSTRITSSMLCAG--RP 270
              |. ||....:.|||....|..||:  |:.:..:|:::...| |....|..:|::|:|||  :.
Zfish   152 SVYS-AGTSSWITGWGDIQAGVNLPAPGILQETMIPVVANDRC-NALLGSGTVTNNMICAGLTQG 214

  Fly   271 SMDSCQGDSGGPLLLSNGVKYFIVGIVSWGVGCGREGYPGVYSRVSKFIPWIKSNL 326
            ..|:||||||||::......:...||.|||.||.....||||:|||::..||.|.:
Zfish   215 GKDTCQGDSGGPMVTRLCTVWVQAGITSWGYGCADPNSPGVYTRVSQYQSWISSKI 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11836	NP_001356925.1	Tryp_SPc	97..325	CDD:238113	86/239 (36%)
prss60.3	XP_002662541.2	Tryp_SPc	36..269	CDD:238113	86/239 (36%)
prss60.3	XP_002662541.2	Somatomedin_B	294..328	CDD:321959
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587874
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6349
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.830