DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11836 and Prss53

DIOPT Version :9

Sequence 1:	NP_001356925.1	Gene:	CG11836 / 43007	FlyBaseID:	FBgn0039272	Length:	333	Species:	Drosophila melanogaster
Sequence 2:	NP_001074737.1	Gene:	Prss53 / 330657	MGIID:	2652890	Length:	552	Species:	Mus musculus

Alignment Length:	263	Identity:	75/263 - (28%)
Similarity:	122/263 - (46%)	Gaps:	40/263 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 ENSSLKNCDCDCGFSNEEIRIVGGKPTGVNQYPWMARIVYDGKFHCGGSLLTKDYVLSAAHC-VK 140
            |||.:.     ||    .:|..|.:...::|:||.||:.:.||..|||:|:::..||:|||| :.
Mouse   290 ENSCVA-----CG----SLRSAGPQAGALSQWPWDARLKHHGKLACGGALVSEVVVLTAAHCFIG 345

  Fly   141 KLRKSKIRVIFGDHDQEITSESQAIQRAVTAVIKHKSFDPDTYNNDIALLRLRKPISFSKIIKPI 205
            :....:..|..|...:|         ..:..:|.|.::.......|:|.|.|.:|::....::|:
Mouse   346 RQTLEEWSVGLGAGPEE---------WGLKQLILHGAYTHPEGGYDVAFLLLAQPVTLGPGLRPL 401

  Fly   206 CLPRYNYD-PAGRIGTVVGWGRTSEGGELPSIVN---QVKVPIMSITECRNQRY----KSTRITS 262
            |||..::. |.|..|.|:  |.|.:.|     :|   .|.|.::....|..|..    ....|..
Mouse   402 CLPYADHHLPDGEHGWVL--GLTQKAG-----INYPQTVPVTVLGPMACSRQHAAPGGTGIPILP 459

  Fly   263 SMLC---AGRPSMDSCQGDSGGPLLLSNGVKYFIVGIVSWGVGCGREGYPGVYSRVSKFIPWIKS 324
            .|:|   .|.|  ..|:|.||.||:......:|:||:.|:|..|.....|.|::.:|.:..|| |
Mouse   460 GMVCTTVVGEP--PHCEGLSGAPLVHEIRGTWFLVGLHSFGDTCQSSAKPAVFAALSAYEDWI-S 521

  Fly   325 NLE 327
            ||:
Mouse   522 NLD 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11836	NP_001356925.1	Tryp_SPc	97..325	CDD:238113	66/239 (28%)
Prss53	NP_001074737.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	27..46
		Tryp_SPc	45..271	CDD:238113
		Tryp_SPc	311..522	CDD:238113	65/229 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920