DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11836 and Tmprss3

DIOPT Version :9

Sequence 1:	NP_001356925.1	Gene:	CG11836 / 43007	FlyBaseID:	FBgn0039272	Length:	333	Species:	Drosophila melanogaster
Sequence 2:	XP_038954650.1	Gene:	Tmprss3 / 309665	RGDID:	1310135	Length:	454	Species:	Rattus norvegicus

Alignment Length:	252	Identity:	92/252 - (36%)
Similarity:	140/252 - (55%)	Gaps:	17/252 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 CDCDCGFSNEEIRIVGGKPTGVNQYPWMARIVYDGKFHCGGSLLTKDYVLSAAHCVKKLRKSK-- 146
            |....|:|.   |||||..:.:.|:||...:.:.|...||||::|..::::|||||..|...|
  Rat   207 CGMRTGYSP---RIVGGNVSSLTQWPWQVSLQFQGYHLCGGSVITPLWIVTAAHCVYDLYHPKSW 268

  Fly   147 -IRV-IFGDHDQEITSESQAIQRAVTAVIKHKSFDPDTYNNDIALLRLRKPISFSKIIKPICLPR 209
             ::| :....|..:.|      ..|..:|.|..:.|....|||||::|.:|::|.:.|:|||||.
  Rat   269 TVQVGLVSLMDSPVPS------HLVEKIIYHSKYKPKRLGNDIALMKLSEPLTFDETIQPICLPN 327

  Fly   210 YNYD-PAGRIGTVVGWGRTSEG-GELPSIVNQVKVPIMSITECRNQRYKSTRITSSMLCAG--RP 270
            ...: |.|::....|||.|.:| |:...::|...||::|...|.::......|:.||||||  :.
  Rat   328 SEENFPDGKLCWTSGWGATEDGAGDASPVLNHAAVPLISNKICNHRDVYGGIISPSMLCAGYLKG 392

  Fly   271 SMDSCQGDSGGPLLLSNGVKYFIVGIVSWGVGCGREGYPGVYSRVSKFIPWIKSNLE 327
            .:|||||||||||:......:.:||..|:|:||.....||||:|::.|:.||...||
  Rat   393 GVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRITSFLDWIHEQLE 449

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11836	NP_001356925.1	Tryp_SPc	97..325	CDD:238113	86/235 (37%)
Tmprss3	XP_038954650.1	LDLa	74..107	CDD:238060
		SRCR_2	112..211	CDD:406055	1/3 (33%)
		Tryp_SPc	216..444	CDD:214473	85/233 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	178	1.000	Inparanoid score	I3918
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm45531
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.860