DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11836 and f10

DIOPT Version :9

Sequence 1:	NP_001356925.1	Gene:	CG11836 / 43007	FlyBaseID:	FBgn0039272	Length:	333	Species:	Drosophila melanogaster
Sequence 2:	NP_958870.3	Gene:	f10 / 282670	ZFINID:	ZDB-GENE-021206-9	Length:	504	Species:	Danio rerio

Alignment Length:	318	Identity:	110/318 - (34%)
Similarity:	166/318 - (52%)	Gaps:	54/318 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 KRTSKFLFDTIFRISSGVSNAFGLSDTEDEVE--------YTENSSLKNCDCDCGFSNEEIRIVG 99
            |:|....|.|     ..::.    |:.|:|.|        |..::.|.| ..|..|...|:.|:.
Zfish   175 KKTRSIFFHT-----PNITE----SENEEETELEATIEPVYNHSNPLNN-QTDSMFGLHELEIIE 229

  Fly   100 GKP--------------TGV----NQYPWMARIVYDGKF-HCGGSLLTKDYVLSAAHCVKKLRKS 145
            .:|              .||    ...||.|.::.:... .|||::||:.::||||||:.:  ..
Zfish   230 EEPILPVVSTAGDGRIVNGVECPPGDCPWQALLINENNMGFCGGTILTEHFILSAAHCMNE--SL 292

  Fly   146 KIRVIFGDHDQEITSESQAIQRAVTAVIKHKSFDPDTYNNDIALLRLRKPISFSKIIKPICLPRY 210
            .|||:.|::| .:..|.:.....|..::.||::.||||:|||||::|.|||.|:|.|.|.|||..
Zfish   293 SIRVVVGEYD-TLVPEGREATHDVDEILIHKNYQPDTYHNDIALIKLSKPIKFTKYIIPACLPEM 356

  Fly   211 NYDPAGRI------GTVVGWGRTSEGGELPSIVNQVKVPIMSITEC-RNQRYKSTRITSSMLCAG 268
            .:  |.|:      |.|.|:||..|||...:|:.::.||.::..:| .:..:|   |:..|.|||
Zfish   357 KF--AERVLMQQDDGLVSGFGRVREGGLSSTILQKLTVPYVNRAKCIESSNFK---ISGRMFCAG 416

  Fly   269 --RPSMDSCQGDSGGPLLLSNGVKYFIVGIVSWGVGCGREGYPGVYSRVSKFIPWIKS 324
              :...|:||||||||.:......:||.|:||||.||.|:|..|||::|||:|.||.:
Zfish   417 YDQEEKDACQGDSGGPHVTRFKNTWFITGVVSWGEGCARKGKYGVYTQVSKYIMWINN 474

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11836	NP_001356925.1	Tryp_SPc	97..325	CDD:238113	96/256 (38%)
f10	NP_958870.3	GLA	19..82	CDD:214503
		EGF_CA	83..119	CDD:238011
		FXa_inhibition	126..161	CDD:291342
		Tryp_SPc	244..472	CDD:214473	92/235 (39%)
		Tryp_SPc	245..474	CDD:238113	94/236 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H30976
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4142
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.940