DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11836 and Klk8

DIOPT Version :9

Sequence 1:	NP_001356925.1	Gene:	CG11836 / 43007	FlyBaseID:	FBgn0039272	Length:	333	Species:	Drosophila melanogaster
Sequence 2:	NP_001311327.1	Gene:	Klk8 / 259277	MGIID:	1343327	Length:	260	Species:	Mus musculus

Alignment Length:	241	Identity:	83/241 - (34%)
Similarity:	126/241 - (52%)	Gaps:	22/241 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    96 RIVGGKPTGVNQYPWMARIVYDGKFHCGGSLLTKDYVLSAAHCVKKLRKSKIRVIFGDHD-QEIT 159
            :|:.|:....:..||.|.:....:..|||.|:...:||:||||    :|.|..|..|||. |...
Mouse    32 KILEGRECIPHSQPWQAALFQGERLICGGVLVGDRWVLTAAHC----KKQKYSVRLGDHSLQSRD 92

  Fly   160 SESQAIQRAVTAVIKHKSF---DPDTYNNDIALLRLRKPISFSKIIKPICLPRYNYDP-AGRIGT 220
            ...|.||  |...|:|..:   :|:.:::||.|:||:...:....:||:.|.  |..| .|:...
Mouse    93 QPEQEIQ--VAQSIQHPCYNNSNPEDHSHDIMLIRLQNSANLGDKVKPVQLA--NLCPKVGQKCI 153

  Fly   221 VVGWGR-TSEGGELPSIVNQVKVPIMSITECRNQRYKSTRITSSMLCAGRPS-MDSCQGDSGGPL 283
            :.|||. ||.....|:.:|..:|.|.|..:|  :|....:||..|:|||..: .|:|||||||||
Mouse   154 ISGWGTVTSPQENFPNTLNCAEVKIYSQNKC--ERAYPGKITEGMVCAGSSNGADTCQGDSGGPL 216

  Fly   284 LLSNGVKYFIVGIVSWGVG-CGREGYPGVYSRVSKFIPWIKSNLEN 328
            :...    .:.||.|||.. ||:...||||:::.::..|||..::|
Mouse   217 VCDG----MLQGITSWGSDPCGKPEKPGVYTKICRYTTWIKKTMDN 258

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11836	NP_001356925.1	Tryp_SPc	97..325	CDD:238113	82/235 (35%)
Klk8	NP_001311327.1	Tryp_SPc	32..252	CDD:214473	79/233 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920