Protein Alignment CG11836 and KLK5

DIOPT Version :9

• Sequence 1: NP_001356925.1
• Gene: CG11836 / 43007
• FlyBaseID: FBgn0039272
• Length: 333
• Species: Drosophila melanogaster
• Sequence 2: NP_001070959.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Alignment Length: 326
• Identity: 91/326 - (27%)
• Similarity: 150/326 - (46%)
• Gaps: 49/326 - (15%)

  Fly     8 FFWMLTANYSSVLSLEYSKGFNESD-AINTIHTGHNKRTSKFLFDTIFRISSGVSNAFGLSDTED 71
            :.|:|.|..:::|     .|..|.. |.|.:...|...|          :.||.:...|....||
Human     8 WMWVLCALITALL-----LGVTEHVLANNDVSCDHPSNT----------VPSGSNQDLGAGAGED 57

  Fly    72 EVEYTENSSLKNCDCDCGFSNEEIRIVGGKPTGVNQYPWMARIVY-DGKFHCGGSLLTKDYVLSA 135
             ....::||               ||:.|....::..||.|.::. ..:.:||..|:...::|:|
Human    58 -ARSDDSSS---------------RIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTA 106

  Fly   136 AHCVKKLRKSKIRVIFGDHDQEITSES-QAIQRAVTAVIKHKSFDPDTYNNDIALLRLRKPISFS 199
            |||    ||...||..|.:......|| |.:.:.|.: |.|..:....::||:.|::|.:.|..:
Human   107 AHC----RKKVFRVRLGHYSLSPVYESGQQMFQGVKS-IPHPGYSHPGHSNDLMLIKLNRRIRPT 166

  Fly   200 KIIKPICLPRYNYDPAGRIGTVVGWGRT-SEGGELPSIVNQVKVPIMSITECRNQRYKSTRITSS 263
            |.::||.:..: ...||....|.|||.| |.....|.::..:.:.::|...|.:...:  :|..:
Human   167 KDVRPINVSSH-CPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPR--QIDDT 228

  Fly   264 MLCAG-RPSMDSCQGDSGGPLLLSNGVKYFIVGIVSWG-VGCGREGYPGVYSRVSKFIPWIKSNL 326
            |.||| :...||||||||||::.:..::    |:|||| ..|.|...||||:.:.||..||:..:
Human   229 MFCAGDKAGRDSCQGDSGGPVVCNGSLQ----GLVSWGDYPCARPNRPGVYTNLCKFTKWIQETI 289

  Fly   327 E 327
            :
Human   290 Q 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11836	NP_001356925.1	Tryp_SPc	97..325	CDD:238113	73/232 (31%)
KLK5	NP_001070959.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		10/56 (18%)
		Tryp_SPc	66..285	CDD:214473	72/230 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920