DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11836 and PRSS54

DIOPT Version :9

Sequence 1:	NP_001356925.1	Gene:	CG11836 / 43007	FlyBaseID:	FBgn0039272	Length:	333	Species:	Drosophila melanogaster
Sequence 2:	NP_001073961.1	Gene:	PRSS54 / 221191	HGNCID:	26336	Length:	395	Species:	Homo sapiens

Alignment Length:	236	Identity:	59/236 - (25%)
Similarity:	108/236 - (45%)	Gaps:	33/236 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   107 QYPWMARIVYDGKFHCG-GSLLTKDYVLSAAHCVKKLRKSKIRVIFGDHDQEITSESQAIQRAVT 170
            ::||:..:......|.. |.:|::.:|||.|..::  .:..|.||.|..:.: .|:....:..|.
Human    52 EFPWVVSLQDSQYTHLAFGCILSEFWVLSIASAIQ--NRKDIVVIVGISNMD-PSKIAHTEYPVN 113

  Fly   171 AVIKHKSFDPDTYNNDIALLRLRKPISFSKIIKPIC-LPRYNYDPAGRIGT-VVGWGRTSEGGE- 232
            .:|.|:.||.::.:|:||||:....:.|..:::.|| |.|..:.|...... |.||..||..|.
Human   114 TIIIHEDFDNNSMSNNIALLKTDTAMHFGNLVQSICFLGRMLHTPPVLQNCWVSGWNPTSATGNH 178

  Fly   233 -LPSIVNQVKV------PIMSI--TECRNQRYKSTRITSSMLCAGRPSMDSCQGDSGGPLLLSNG 288
             ..|::.::.|      |:..:  |||.:...:.|:             .:|.||.|.|::..
Human   179 MTMSVLRKIFVKDLDMCPLYKLQKTECGSHTKEETK-------------TACLGDPGSPMMCQ-- 228

  Fly   289 VKYFIVGIVSWGVGCGREGYPG--VYSRVSKFIPWIKSNLE 327
            ::.|.:.::...:..|.|..||  :|::|..:..||.|..|
Human   229 LQQFDLWVLRGVLNFGGETCPGLFLYTKVEDYSKWITSKAE 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11836	NP_001356925.1	Tryp_SPc	97..325	CDD:238113	57/232 (25%)
PRSS54	NP_001073961.1	Tryp_SPc	52..264	CDD:214473	55/229 (24%)
		Tryp_SPc	52..264	CDD:238113	55/229 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	324..348
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910