Protein Alignment CG11836 and F12

DIOPT Version :10

• Sequence 1: NP_001356925.1
• Gene: CG11836 / 43007
• FlyBaseID: FBgn0039272
• Length: 333
• Species: Drosophila melanogaster
• Sequence 2: NP_000496.2
• Gene: F12 / 2161
• HGNCID: 3530
• Length: 615
• Species: Homo sapiens
• Alignment Length: 266
• Identity: 87/266 - (32%)
• Similarity: 136/266 - (51%)
• Gaps: 22/266 - (8%)

  Fly    79 SSLKNCDCDCG-----FSNEEIRIVGGKPTGVNQYPWMARIVYDGKFHCGGSLLTKDYVLSAAHC 138
            |..:|....||     ..:...|:|||.......:|::|.: |.|...|.|||:...:||:||||
Human   350 SLTRNGPLSCGQRLRKSLSSMTRVVGGLVALRGAHPYIAAL-YWGHSFCAGSLIAPCWVLTAAHC 413

  Fly   139 VK-KLRKSKIRVIFGDHDQEITSE-SQAIQRAVTAVIKHKSFDPDTYNNDIALLRLRKPIS---- 197
            :: :.....:.|:.|...:..:.| .|.:  ||.:...|::|.|.:|.:|:|||||::...
Human   414 LQDRPAPEDLTVVLGQERRNHSCEPCQTL--AVRSYRLHEAFSPVSYQHDLALLRLQEDADGSCA 476

  Fly   198 -FSKIIKPICLPRYNYDPA-GRIGTVVGWGRTSEGG-ELPSIVNQVKVPIMSITECRNQRYKSTR 259
             .|..::|:|||.....|: ..:..|.|||...||. |..|.:.:.:||.:|:..|.......:.
Human   477 LLSPYVQPVCLPSGAARPSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVHGSS 541

  Fly   260 ITSSMLCAG--RPSMDSCQGDSGGPLLLSNGV---KYFIVGIVSWGVGCGREGYPGVYSRVSKFI 319
            |...|||||  ....|:|||||||||:..:..   :..:.||:|||.|||....||||:.|:.::
Human   542 ILPGMLCAGFLEGGTDACQGDSGGPLVCEDQAAERRLTLQGIISWGSGCGDRNKPGVYTDVAYYL 606

  Fly   320 PWIKSN 325
            .||:.:
Human   607 AWIREH 612

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11836	NP_001356925.1	Tryp_SPc	97..325	CDD:238113	82/241 (34%)
F12	NP_000496.2	FN2	41..88	CDD:128373
		EGF_CA	96..131	CDD:238011
		FN1	133..173	CDD:238018
		EGF	178..206	CDD:394967
		Kringle	217..295	CDD:395005
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	298..359		2/8 (25%)
		Tryp_SPc	373..612	CDD:238113	82/241 (34%)