DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11836 and St14

DIOPT Version :9

Sequence 1:	NP_001356925.1	Gene:	CG11836 / 43007	FlyBaseID:	FBgn0039272	Length:	333	Species:	Drosophila melanogaster
Sequence 2:	XP_036010597.1	Gene:	St14 / 19143	MGIID:	1338881	Length:	875	Species:	Mus musculus

Alignment Length:	318	Identity:	105/318 - (33%)
Similarity:	168/318 - (52%)	Gaps:	37/318 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 GFNES--DAINTIHTGHNKRTSKFLFDTIFRISSGVSNAFGLSDTEDEVEYTENSSLKNCDCDCG 89
            |.:|:  |::|.:      ..:|:    .:|..:|:..:.|..:.:.:.:.::.|..|||||...
Mouse   573 GSDEASCDSVNVV------SCTKY----TYRCQNGLCLSKGNPECDGKTDCSDGSDEKNCDCGLR 627

  Fly    90 FSNEEIRIVGGKPTGVNQYPWMARIVYDGKFH-CGGSLLTKDYVLSAAHCVKKLRKSKIRVIFGD 153
            ...::.|:|||......::||...:...|:.| ||.||::.|:::|||||.:..:..|    :.|
Mouse   628 SFTKQARVVGGTNADEGEWPWQVSLHALGQGHLCGASLISPDWLVSAAHCFQDDKNFK----YSD 688

  Fly   154 H----------DQEITSESQAIQRAVTAVIKHKSFDPDTYNNDIALLRLRKPISFSKIIKPICLP 208
            :          ||...|.|...:..:..:|.|.||:..|::.|||||.|.|.:.:|.:::|||||
Mouse   689 YTMWTAFLGLLDQSKRSASGVQELKLKRIITHPSFNDFTFDYDIALLELEKSVEYSTVVRPICLP 753

  Fly   209 RYNY-DPAGRIGTVVGWGRTSEGGELPSIVNQVKVPIMSITECRNQRYKSTRITSSMLCAGRPS- 271
            ...: .|||:...|.|||.|.|||....|:.:.::.:::.|.|.:  ....:||..|:|.|..|
Mouse   754 DATHVFPAGKAIWVTGWGHTKEGGTGALILQKGEIRVINQTTCED--LMPQQITPRMMCVGFLSG 816

  Fly   272 -MDSCQGDSGGPLLLSNGVK---YFIVGIVSWGVGCGREGYPGVYSRVSKFIPWIKSN 325
             :||||||||||  ||:..|   .|..|:||||.||.:...||||:|:.....|||.:
Mouse   817 GVDSCQGDSGGP--LSSAEKDGRMFQAGVVSWGEGCAQRNKPGVYTRLPVVRDWIKEH 872

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11836	NP_001356925.1	Tryp_SPc	97..325	CDD:238113	90/244 (37%)
St14	XP_036010597.1	SEA	108..198	CDD:396113
		CUB	247..352	CDD:238001
		CUB	360..464	CDD:238001
		LDLa	474..506	CDD:238060
		LDLa	512..543	CDD:238060
		LDLa	545..579	CDD:238060	2/5 (40%)
		LDLa	587..622	CDD:238060	6/38 (16%)
		Tryp_SPc	635..872	CDD:238113	90/244 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820