DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11836 and svh-1

DIOPT Version :9

Sequence 1:	NP_001356925.1	Gene:	CG11836 / 43007	FlyBaseID:	FBgn0039272	Length:	333	Species:	Drosophila melanogaster
Sequence 2:	NP_501379.2	Gene:	svh-1 / 182375	WormBaseID:	WBGene00006620	Length:	951	Species:	Caenorhabditis elegans

Alignment Length:	365	Identity:	106/365 - (29%)
Similarity:	163/365 - (44%)	Gaps:	91/365 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 NTIHTGHNKRTSKFLFDTIFR--------------ISSGVSNAFGLSDTEDEVEYTENSSLK--- 82
            |:....:...||.:| :.:||              ||:.:.:|..|.  |.....:.|:::.
Worm   596 NSFRLTNGSDTSGYL-EVLFRSRWEPICADHLNGKISNSICDAMRLG--EHGFILSTNATISSGY 657

  Fly    83 --NCDCDC--------------------GFSNEE-------------------IRIVGGKPTGVN 106
              |||.||                    |.|:..                   .|:|||..|...
Worm   658 NVNCDVDCSIRRSSSCTRHARISCISQNGMSSASQCGLRYVEVNARDAAKSRIARVVGGFETVPG 722

  Fly   107 QYPWMA--RIVYDGKFHCGGSLLTKDYVLSAAHCVKK-LRKSKIRVIFGDHDQEITSESQAIQRA 168
            .:||.|  |.......|||.|:|.|.::::||||.:: .|.|...|:.||.|...|..::.|
Worm   723 AFPWTAALRNKATKAHHCGASILDKTHLITAAHCFEEDERVSSYEVVVGDWDNNQTDGNEQI--- 784

  Fly   169 VTAVIKHKSFDP---DTYNNDIALLRLRKP-ISFSKIIKPICLPR--YNYDPAGRIGTVVGWGRT 227
              ..::...|.|   |.:::|||:|.:..| |.|::..:|||||.  :.|.| ||...|.|||
Worm   785 --FYLQRIHFYPLYKDIFSHDIAILEIPYPGIEFNEYAQPICLPSKDFVYTP-GRQCVVSGWG-- 844

  Fly   228 SEGGELPSIVNQVKVPIMSITECRNQRYKSTRITSSM----LCAG--RPSMDSCQGDSGGPLLL- 285
            |.|......:....:||::..:|.|    |::|.|||    .|||  ...:||||||||||...
Worm   845 SMGLRYAERLQAALIPIINRFDCVN----SSQIYSSMSRSAFCAGYLEGGIDSCQGDSGGPFACR 905

  Fly   286 -SNGVKYFIVGIVSWGVGCGREGYPGVYSRVSKFIPWIKS 324
             .:|. :.:.|::|||.||.::..||:|:.|:.::.||.:
Worm   906 REDGA-FVLAGVISWGDGCAQKKQPGIYTMVAPYLSWISA 944

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11836	NP_001356925.1	Tryp_SPc	97..325	CDD:238113	86/245 (35%)
svh-1	NP_501379.2	KR	227..306	CDD:214527
		LDLa	320..355	CDD:238060
		PAN_AP_HGF	373..434	CDD:238532
		LDLa	558..590	CDD:197566
		SRCR_2	599..681	CDD:382996	16/84 (19%)
		Tryp_SPc	713..945	CDD:238113	86/245 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910