Protein Alignment CG11836 and TMPRSS11B

DIOPT Version :10

• Sequence 1: NP_001356925.1
• Gene: CG11836 / 43007
• FlyBaseID: FBgn0039272
• Length: 333
• Species: Drosophila melanogaster
• Sequence 2: NP_872308.2
• Gene: TMPRSS11B / 132724
• HGNCID: 25398
• Length: 416
• Species: Homo sapiens
• Alignment Length: 345
• Identity: 111/345 - (32%)
• Similarity: 161/345 - (46%)
• Gaps: 44/345 - (12%)

  Fly    11 MLTANYSSVLSLEYSKGFNESDAINTIHTGHNKRTS---KFLFDTIFRISSGVS----------- 61
            ||.|..:|.:..||.|    |:.|..:...:.....   ||.|..    :.|||
Human    81 MLNAFQNSSIYKEYVK----SEVIKLLPNANGSNVQLQLKFKFPP----AEGVSMRTKIKAKLHQ 137

  Fly    62 ---------NAFGLSDTEDEVEYTENSSLKNCDCDCGFSNEEI---RIVGGKPTGVNQYPWMARI 114
                     ||...|....|:....:..|.|..|....:|..|   :||.||.:....:||.|.:
Human   138 MLKNNMASWNAVPASIKLMEISKAASEMLTNNCCGRQVANSIITGNKIVNGKSSLEGAWPWQASM 202

  Fly   115 VYDGKFHCGGSLLTKDYVLSAAHCVKKLRKSK-IRVIFGDHDQEITSESQAIQRAVTAVIKHKSF 178
            .:.|:.:||.||::..::||||||..|...|| ..|.||     |......:.|.|..:|.|:::
Human   203 QWKGRHYCGASLISSRWLLSAAHCFAKKNNSKDWTVNFG-----IVVNKPYMTRKVQNIIFHENY 262

  Fly   179 DPDTYNNDIALLRLRKPISFSKIIKPICLPRYNYDPAGRIGTVV-GWGRTSEGGELPSIVNQVKV 242
            .....::||||::|.:.:||::.|:.||||......:.....|| |||.....|..|.|:.:..:
Human   263 SSPGLHDDIALVQLAEEVSFTEYIRKICLPEAKMKLSENDNVVVTGWGTLYMNGSFPVILQEDFL 327

  Fly   243 PIMSITECRNQRYKSTRITSSMLCAGRPS--MDSCQGDSGGPLLLSNGVK-YFIVGIVSWGVGCG 304
            .|:....|......|..:|.:|||||..|  .|:||.||||||...:... :.:|||||||.|||
Human   328 KIIDNKICNASYAYSGFVTDTMLCAGFMSGEADACQNDSGGPLAYPDSRNIWHLVGIVSWGDGCG 392

  Fly   305 REGYPGVYSRVSKFIPWIKS 324
            ::..||||:||:.:..||.|
Human   393 KKNKPGVYTRVTSYRNWITS 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11836	NP_001356925.1	Tryp_SPc	97..325	CDD:238113	87/233 (37%)
TMPRSS11B	NP_872308.2	SEA	45..142	CDD:460188	15/68 (22%)
		Tryp_SPc	185..413	CDD:238113	87/233 (37%)