DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG11836 and KLK8

DIOPT Version :9

Sequence 1:NP_001356925.1 Gene:CG11836 / 43007 FlyBaseID:FBgn0039272 Length:333 Species:Drosophila melanogaster
Sequence 2:NP_653088.1 Gene:KLK8 / 11202 HGNCID:6369 Length:305 Species:Homo sapiens


Alignment Length:245 Identity:87/245 - (35%)
Similarity:123/245 - (50%) Gaps:34/245 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    93 EEIRIVGGKPTGVNQYPWMARIVYDGKFHCGGSLLTKDYVLSAAHCVKKLRKSKIRVIFGDH--- 154
            :|.:::||.....:..||.|.:....:..|||.|:..::||:||||    :|.|..|..|||   
Human    74 QEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHC----KKPKYTVRLGDHSLQ 134

  Fly   155 -----DQEITSESQAIQRAVTAVIKH---KSFDPDTYNNDIALLRLRKPISFSKIIKPICLPRYN 211
                 :|||         .|...|.|   .|.|.:.:|:|:.||:||...|....:|||.|..:.
Human   135 NKDGPEQEI---------PVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHC 190

  Fly   212 YDPAGRIGTVVGWGR-TSEGGELPSIVNQVKVPIMSITECRNQRYKSTRITSSMLCAG-RPSMDS 274
            ..| |:..||.|||. ||.....|..:|..:|.|....:|.: .|.. :||..|:||| ....|:
Human   191 TQP-GQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCED-AYPG-QITDGMVCAGSSKGADT 252

  Fly   275 CQGDSGGPLLLSNGVKYFIVGIVSWGVG-CGREGYPGVYSRVSKFIPWIK 323
            |||||||||:....::    ||.|||.. |||...||||:.:.:::.|||
Human   253 CQGDSGGPLVCDGALQ----GITSWGSDPCGRSDKPGVYTNICRYLDWIK 298

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG11836NP_001356925.1 Tryp_SPc 97..325 CDD:238113 86/241 (36%)
KLK8NP_653088.1 Tryp_SPc 77..297 CDD:214473 83/239 (35%)
Tryp_SPc 78..300 CDD:238113 86/241 (36%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D433637at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.920

Return to query results.
Submit another query.