DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11836 and Klk5

DIOPT Version :9

Sequence 1:	NP_001356925.1	Gene:	CG11836 / 43007	FlyBaseID:	FBgn0039272	Length:	333	Species:	Drosophila melanogaster
Sequence 2:	XP_038952099.1	Gene:	Klk5 / 102546758	RGDID:	1593461	Length:	293	Species:	Rattus norvegicus

Alignment Length:	286	Identity:	87/286 - (30%)
Similarity:	140/286 - (48%)	Gaps:	37/286 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 GLSD--TEDEVEYTENSSLK---------NCDCDCG---FSNEEIRIVGGKPTGVNQYPWM-ARI 114
            |:|:  ..|:|...:|||..         |.|.:.|   .|:...|||.|.....:..||. |.:
  Rat    22 GVSELALADDVASCDNSSGTKPSGTNRDLNTDSNSGEDTRSDSSSRIVNGSDCPKDTQPWQGALL 86

  Fly   115 VYDGKFHCGGSLLTKDYVLSAAHCVKKLRKSKIRVIFGDHDQEITSES-QAIQRAVTAVIKHKSF 178
            :...|.:||..|:...::|:||||    ||...|:..|.|......|| |.:.:.:.: |.|..:
  Rat    87 LGPNKLYCGAVLINPQWLLTAAHC----RKPVFRIRLGHHSMSPVYESGQQMFQGIKS-IPHPGY 146

  Fly   179 DPDTYNNDIALLRLRKPISFSKIIKPICLPRYNYDPAGRIGT---VVGWGRTSEG-GELPSIVNQ 239
            ....::||:.|:::.:.|..|..:||:.:.    ....:.||   |.|||.||.. ...|.::..
  Rat   147 SHPGHSNDLMLIKMNRKIRASHSVKPVEIT----SDCPKEGTRCMVSGWGTTSSSHNNFPKVLQC 207

  Fly   240 VKVPIMSITECRNQRYKSTRITSSMLCAG-RPSMDSCQGDSGGPLLLSNGVKYFIVGIVSWG-VG 302
            :.:.::|...|:|. |.. :|..:|.||| ....||||||||||::.:..::    |:|||| ..
  Rat   208 LDITVLSEERCKNS-YPG-QIDKTMFCAGDEAGRDSCQGDSGGPVICNGKLQ----GLVSWGDFP 266

  Fly   303 CGREGYPGVYSRVSKFIPWIKSNLEN 328
            |.:...||||:.:.:|:||||..:.:
  Rat   267 CAQPNRPGVYTNLCEFVPWIKDTIHS 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11836	NP_001356925.1	Tryp_SPc	97..325	CDD:238113	75/235 (32%)
Klk5	XP_038952099.1	Tryp_SPc	67..286	CDD:214473	73/233 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010