DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11839 and ZNF830

DIOPT Version :9

Sequence 1:	NP_733077.3	Gene:	CG11839 / 43006	FlyBaseID:	FBgn0039271	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_443089.3	Gene:	ZNF830 / 91603	HGNCID:	28291	Length:	372	Species:	Homo sapiens

Alignment Length:	356	Identity:	90/356 - (25%)
Similarity:	147/356 - (41%)	Gaps:	109/356 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MNNGNIKRLQK---KLSVSKKPAVTVDSPLAKYDSSGILTCIICRIPIKPN-VWKVHINSKQHKL 61
            :|...::||.|   :||.|:|   .::||.|||:..|.|:|.:|..|:|.. :|:.|:..|||:.
Human    16 INQEELRRLMKEKQRLSTSRK---RIESPFAKYNRLGQLSCALCNTPVKSELLWQTHVLGKQHRE 77

  Fly    62 NVDQAKQNK--------------------------VEKPVTTTAPK------------DPTGPST 88
            .|.:.|..|                          |::...|..|:            |..|...
Human    78 KVAELKGAKEASQGSSASSAPHSVKRKAPDADDQDVKRAKATLVPQVQPSTSAWTTNFDKIGKEF 142

  Fly    89 KTSAPAKNS--STLPDKTPQSSQEKH-------------PPLIQEKTAQGNASSKPE-------- 130
            ..:.|:|.|  |.|||...:..:|:.             .||...:..:.:.||..|
Human   143 IRATPSKPSGLSLLPDYEDEEEEEEEEEGDGERKRGDASKPLSDAQGKEHSVSSSREVTSSVLPN 207

  Fly   131 -------------------------------NETTVEKLPEKFFDED----KTNKSEAARLQ-DE 159
                                           .|.|.|.|||.|||:.    :..|.:|.:.| |:
Human   208 DFFSTNPPKAPIIPHSGSIEKAEIHEKVVERRENTAEALPEGFFDDPEVDARVRKVDAPKDQMDK 272

  Fly   160 EWQRFQQEIKRADTESSEIVADEQEDINLKRHIKEIDEQIDNWKRFIKINDQKKVLLSKKRRVDP 224
            ||..||:.:::.:|.|..|||:|.|:..|.|.|.||||||:.::|..|:.:::..:.:|.:.:..
Human   273 EWDEFQKAMRQVNTISEAIVAEEDEEGRLDRQIGEIDEQIECYRRVEKLRNRQDEIKNKLKEILT 337

  Fly   225 KMEV---DPELSSSEEDCSVDDLF--DWRTK 250
            ..|:   :.|.:.|:::..:.||.  |||.|
Human   338 IKELQKKEEENADSDDEGELQDLLSQDWRVK 368

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11839	NP_733077.3	None
ZNF830	NP_443089.3	ZnF_U1	49..82	CDD:197732	12/32 (38%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	78..126		6/47 (13%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	143..225		13/81 (16%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158862
Domainoid	1	1.000	80	1.000	Domainoid score	I8599
eggNOG	1	0.900	-	-		E1_KOG3032
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41655
Inparanoid	1	1.050	81	1.000	Inparanoid score	I5217
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60282
OrthoDB	1	1.010	-	-		D1458826at2759
OrthoFinder	1	1.000	-	-		FOG0006403
OrthoInspector	1	1.000	-	-		oto91664
orthoMCL	1	0.900	-	-		OOG6_106584
Panther	1	1.100	-	-	LDO	PTHR13278
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5351
SonicParanoid	1	1.000	-	-		X6139
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800