DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Stt3B and STT3B

DIOPT Version :9

Sequence 1:	NP_524494.1	Gene:	Stt3B / 43005	FlyBaseID:	FBgn0011336	Length:	774	Species:	Drosophila melanogaster
Sequence 2:	NP_174675.2	Gene:	STT3B / 840312	AraportID:	AT1G34130	Length:	735	Species:	Arabidopsis thaliana

Alignment Length:	746	Identity:	397/746 - (53%)
Similarity:	509/746 - (68%)	Gaps:	46/746 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MNRTPKMLNSKVAGYSS----------LITFAILLIAWLAGFSSRLFAVIRFESIIHEFDPWFNY 55
            |...|.:||:....:.|          |:..:||.:.::..|.:|||:|:|:||:||||||:|||
plant    13 MATKPDLLNTSFFSFKSLKLKTKQQELLLRISILGLVYILAFIARLFSVLRYESMIHEFDPYFNY 77

  Fly    56 RATAYMVQNGWYNFLNWFDERAWYPLGRIVGGTVYPGLMITSGGIHWLLHVLNIPVHIRDICVFL 120
            |.|.::.:.|:|.|.||||..:|||||||:|||:|||||:|:..|:|.|..|...||||::||..
plant    78 RTTLFLTEKGFYEFWNWFDSESWYPLGRIIGGTLYPGLMVTAALIYWTLRFLRFFVHIREVCVLT 142

  Fly   121 APIFSGLTSISTYLLTKELWSAGAGLFAASFIAIVPGYISRSVAGSYDNEGIAIFALQFTYFLWV 185
            ||.|:..|::..|...||||..||||.||..|||.|||||||||||||||.:|||||..|::|:|
plant   143 APFFASNTTLVAYFFGKELWDTGAGLVAAVLIAICPGYISRSVAGSYDNEAVAIFALLLTFYLFV 207

  Fly   186 RSVKTGSVFWSAAAALSYFYMVSAWGGYVFIINLIPLHVFVLLIMGRYSPRLLTSYSTFYILGLL 250
            ::|.|||:.|:.|:|..|||||||||||||||||:||:|.||||.||||.||..:|:..||||:|
plant   208 KAVNTGSLAWALASAFGYFYMVSAWGGYVFIINLVPLYVLVLLITGRYSMRLYIAYNCMYILGML 272

  Fly   251 FSMQIPFVGFQPIRTSEHMAALGVFVLLMAVATLRHLQSVLSRNEFRKLF---------IVGGLL 306
            .:|||.|||||.:::.|||.|:|||:|:.....|..::..|:..:..:.|         :|||:.
plant   273 LAMQIRFVGFQHVQSGEHMGAMGVFLLMQVFYFLDWVKYQLNDTKLFQTFLRITVTSAILVGGVA 337

  Fly   307 VGVGVFVAVVVLTMLGVVAPWSGRFYSLWDTGYAKIHIPIIASVSEHQPTTWFSFFFDLHILVCA 371
            ||||        |..|.::||:||||||.|..|||.||||||||||||||.|.||.||.|||:..
plant   338 VGVG--------TASGYISPWTGRFYSLLDPTYAKDHIPIIASVSEHQPTAWSSFMFDYHILLFL 394

  Fly   372 FPVGVWYCIKQINDERVFVVLYAISAVYFAGVMVRLMLTLTPVVCMLAGVAFSGLLDVFLQEDSS 436
            ||.|:::|.|::.|..:|:|:|.::::|||||||||:|..||.||:::.:|.|..:
plant   395 FPAGLYFCFKRLTDATIFIVMYGLTSLYFAGVMVRLILVATPAVCLISAIAVSATI--------- 450

  Fly   437 KRMGTAISAATEVDEAEDSIEKKTLYDKAGKLKHRTKHDAQQDTGVSSNLKSIVILAVLMLLMMF 501
            |.:.:.:....:|.:...:       ..||..|..:|....|......|....:::.|..||..:
plant   451 KNLTSLLRTKQKVSQTGST-------KGAGSSKASSKVTLDQSQPFQKNGAIALLVGVFYLLSRY 508

  Fly   502 AVHCTWVTSNAYSSPSIVLAFHNSQDGSRNILDDFREAYYWLSQNTADDARVMSWWDYGYQIAGM 566
            |:||||||:.||||||||||...:. |:|.|.||:|||||||.||||.||::||||||||||..|
plant   509 AIHCTWVTAEAYSSPSIVLAARGAH-GNRIIFDDYREAYYWLRQNTATDAKIMSWWDYGYQITAM 572

  Fly   567 ANRTTLVDNNTWNNSHIALVGKAMSSTEEKSYEIMTSLDVDYVLVIFGGVIGYSGDDINKFLWMV 631
            .|||.:||||||||:|||.||:||||.|:.:|:||.||||:||||:||||.|||.||||||||||
plant   573 GNRTVIVDNNTWNNTHIATVGRAMSSYEDDAYDIMRSLDVNYVLVVFGGVTGYSSDDINKFLWMV 637

  Fly   632 RIAEGEHPKDIKESDYFTDRGEFRVDAEGAPALLNCLMYKLSYYRFGELKLDYRGPSGYDRTRNA 696
            ||..|..|. |||.||..: ||||||...:|.:||||||||.|||||||..:|..|.||||.|..
plant   638 RIGGGVFPV-IKEPDYLVN-GEFRVDKGASPKMLNCLMYKLCYYRFGELTTEYGKPPGYDRARGV 700

  Fly   697 VIGNKDFDLTYLEEAYTTEHWLVRIYRVKKP 727
            .|||||..|.:|||||||.:|:|||||||.|
plant   701 EIGNKDIKLEHLEEAYTTSNWIVRIYRVKPP 731

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Stt3B	NP_524494.1	Stt3	10..768	CDD:224206	393/737 (53%)
Stt3B	NP_524494.1	STT3	18..514	CDD:280649	245/504 (49%)
STT3B	NP_174675.2	Stt3	28..733	CDD:224206	393/731 (54%)
STT3B	NP_174675.2	STT3	40..521	CDD:280649	245/504 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62160
OrthoDB	1	1.010	-	-		D187775at2759
OrthoFinder	1	1.000	-	-		FOG0001875
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100521
Panther	1	1.100	-	-	O	PTHR13872
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1235
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.790