DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Stt3B and Stt3a

DIOPT Version :9

Sequence 1:	NP_524494.1	Gene:	Stt3B / 43005	FlyBaseID:	FBgn0011336	Length:	774	Species:	Drosophila melanogaster
Sequence 2:	NP_001128221.1	Gene:	Stt3a / 500972	RGDID:	1565793	Length:	705	Species:	Rattus norvegicus

Alignment Length:	721	Identity:	418/721 - (57%)
Similarity:	531/721 - (73%)	Gaps:	53/721 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 SLITFAILLIAWLAGFSSRLFAVIRFESIIHEFDPWFNYRATAYMVQNGWYNFLNWFDERAWYPL 81
            :|:...||.:|.:..||:|||||:||||:||||||:||||.|.::.:.|:|.|.||||:||||||
  Rat    16 TLLKLLILSMAAVLSFSTRLFAVLRFESVIHEFDPYFNYRTTRFLAEEGFYKFHNWFDDRAWYPL 80

  Fly    82 GRIVGGTVYPGLMITSGGIHWLLHVLNIPVHIRDICVFLAPIFSGLTSISTYLLTKELWSAGAGL 146
            |||:|||:||||||||..|:.:||..:|.:.||::||||||:||..|:|.||.|||||..|||||
  Rat    81 GRIIGGTIYPGLMITSAAIYHVLHFFHITIDIRNVCVFLAPLFSSFTTIVTYHLTKELKDAGAGL 145

  Fly   147 FAASFIAIVPGYISRSVAGSYDNEGIAIFALQFTYFLWVRSVKTGSVFWSAAAALSYFYMVSAWG 211
            .||:.||:|||||||||||||||||||||.:..||::|:::|||||::|:|..||:||||||:||
  Rat   146 LAAAMIAVVPGYISRSVAGSYDNEGIAIFCMLLTYYMWIKAVKTGSIYWAAKCALAYFYMVSSWG 210

  Fly   212 GYVFIINLIPLHVFVLLIMGRYSPRLLTSYSTFYILGLLFSMQIPFVGFQPIRTSEHMAALGVFV 276
            ||||:||||||||.||::.||:|.|:..:|.|.|.||.:.||||.||||||:.:||||||.|||.
  Rat   211 GYVFLINLIPLHVLVLMLTGRFSHRIYVAYCTVYCLGTILSMQISFVGFQPVLSSEHMAAFGVFG 275

  Fly   277 LLMAVATLRHLQSVLSRNEFRKLF-----IVGGLLVGVGVFVAVVVLTMLGVVAPWSGRFYSLWD 336
            |....|.:.:|:|.|:..:|..||     :||.:|:.||   |:::||  |.::||:||||||.|
  Rat   276 LCQIHAFVDYLRSKLNPQQFEVLFRSVISLVGFVLLTVG---ALLMLT--GKISPWTGRFYSLLD 335

  Fly   337 TGYAKIHIPIIASVSEHQPTTWFSFFFDLHILVCAFPVGVWYCIKQINDERVFVVLYAISAVYFA 401
            ..|||.:|||||||||||||||.|::|||.:||..||||::||...::|.|:|:::|.::::||:
  Rat   336 PSYAKNNIPIIASVSEHQPTTWSSYYFDLQLLVFMFPVGLYYCFSNLSDARIFIIMYGVTSMYFS 400

  Fly   402 GVMVRLMLTLTPVVCMLAGVAFSGLLDVFLQE-DSSKRMGTAISAATEVDEAEDSIEKKTLYDKA 465
            .|||||||.|.||:|:|:|:..|.:|..:::. |.|:.                        ||.
  Rat   401 AVMVRLMLVLAPVMCILSGIGVSQVLSTYMKNLDISRP------------------------DKK 441

  Fly   466 GKLKHRTKHDAQQDT--GVSSNLKSIVILAVLMLLMMFAVHCTWVTSNAYSSPSIVLAFHNSQDG 528
            .|        .|||:  .:.:.:.|.:||.:...|:.:..|.|||||.|||||||||:.... ||
  Rat   442 SK--------KQQDSTYPIKNEVASGMILVMAFFLITYTFHSTWVTSEAYSSPSIVLSARGG-DG 497

  Fly   529 SRNILDDFREAYYWLSQNTADDARVMSWWDYGYQIAGMANRTTLVDNNTWNNSHIALVGKAMSST 593
            ||.|.||||||||||..||.:||:|||||||||||..|||||.|||||||||:||:.||:||:||
  Rat   498 SRIIFDDFREAYYWLRHNTPEDAKVMSWWDYGYQITAMANRTILVDNNTWNNTHISRVGQAMAST 562

  Fly   594 EEKSYEIMTSLDVDYVLVIFGGVIGYSGDDINKFLWMVRIA----EGEHPKDIKESDYFTDRGEF 654
            |||:||||..|||.||||||||:.|||.||||||||||||.    .|.|   |||:||:|..|||
  Rat   563 EEKAYEIMRELDVSYVLVIFGGLTGYSSDDINKFLWMVRIGGSTETGRH---IKENDYYTPTGEF 624

  Fly   655 RVDAEGAPALLNCLMYKLSYYRFGELKLDYRGPSGYDRTRNAVIGNKDFDLTYLEEAYTTEHWLV 719
            |||.||:|.||||||||:.|||||::..:.:.|.|:||.|||.||||||:|..||||||||||||
  Rat   625 RVDREGSPVLLNCLMYKMCYYRFGQVYTEAKRPPGFDRVRNAEIGNKDFELDVLEEAYTTEHWLV 689

  Fly   720 RIYRVK 725
            |||:||
  Rat   690 RIYKVK 695

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Stt3B	NP_524494.1	Stt3	10..768	CDD:224206	418/721 (58%)
Stt3B	NP_524494.1	STT3	18..514	CDD:280649	264/503 (52%)
Stt3a	NP_001128221.1	STT3	17..484	CDD:396873	264/503 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D111618at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910