DRSC - DRSC Integrative Ortholog Prediction Tool

DRSC/TRiP Functional Genomics Resources

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Protein Alignment Stt3B and STT3A

DIOPT Version :10

Sequence 1:	NP_524494.1	Gene:	Stt3B / 43005	FlyBaseID:	FBgn0011336	Length:	774	Species:	Drosophila melanogaster
Sequence 2:	NP_689926.1	Gene:	STT3A / 3703	HGNCID:	6172	Length:	705	Species:	Homo sapiens

Alignment Length:	13	Identity:	8/13 - (61%)
Similarity:	9/13 - (69%)	Gaps:	1/13 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   511 VC-VTIVCTYFLL 522
            || |.|||.:.||
Human   305 VCAVWIVCCFLLL 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Stt3B	NP_524494.1	STT3	18..514	CDD:396873	2/3 (67%)
STT3A	NP_689926.1	STT3	17..484	CDD:396873	8/13 (62%)
		DXD motif 1. /evidence=ECO:0000250\|UniProtKB:Q5HTX9	47..49
		DXD motif 2. /evidence=ECO:0000250\|UniProtKB:P39007	167..169
		SVSE motif. /evidence=ECO:0000250\|UniProtKB:Q5HTX9	348..351
		WWDYG motif. /evidence=ECO:0000250\|UniProtKB:P39007	525..529
		Interacts with target acceptor peptide in protein substrate. /evidence=ECO:0000250\|UniProtKB:B9KDD4	525..527
		DK motif. /evidence=ECO:0000250\|UniProtKB:P39007	592..599
Blue background indicates that the domain is not in the aligned region.

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