Protein Alignment Stt3B and Stt3a

DIOPT Version :10

• Sequence 1: NP_524494.1
• Gene: Stt3B / 43005
• FlyBaseID: FBgn0011336
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: NP_032434.3
• Gene: Stt3a / 16430
• MGIID: 105124
• Length: 705
• Species: Mus musculus
• Alignment Length: 721
• Identity: 418/721 - (57%)
• Similarity: 531/721 - (73%)
• Gaps: 53/721 - (7%)

  Fly    17 SLITFAILLIAWLAGFSSRLFAVIRFESIIHEFDPWFNYRATAYMVQNGWYNFLNWFDERAWYPL 81
            :|:...||.:|.:..||:|||||:||||:||||||:||||.|.::.:.|:|.|.||||:||||||
Mouse    16 TLLKLLILSMAAVLSFSTRLFAVLRFESVIHEFDPYFNYRTTRFLAEEGFYKFHNWFDDRAWYPL 80

  Fly    82 GRIVGGTVYPGLMITSGGIHWLLHVLNIPVHIRDICVFLAPIFSGLTSISTYLLTKELWSAGAGL 146
            |||:|||:||||||||..|:.:||..:|.:.||::||||||:||..|:|.||.|||||..|||||
Mouse    81 GRIIGGTIYPGLMITSAAIYHVLHFFHITIDIRNVCVFLAPLFSSFTTIVTYHLTKELKDAGAGL 145

  Fly   147 FAASFIAIVPGYISRSVAGSYDNEGIAIFALQFTYFLWVRSVKTGSVFWSAAAALSYFYMVSAWG 211
            .||:.||:|||||||||||||||||||||.:..||::|:::|||||::|:|..||:||||||:||
Mouse   146 LAAAMIAVVPGYISRSVAGSYDNEGIAIFCMLLTYYMWIKAVKTGSIYWAAKCALAYFYMVSSWG 210

  Fly   212 GYVFIINLIPLHVFVLLIMGRYSPRLLTSYSTFYILGLLFSMQIPFVGFQPIRTSEHMAALGVFV 276
            ||||:||||||||.||::.||:|.|:..:|.|.|.||.:.||||.||||||:.:||||||.|||.
Mouse   211 GYVFLINLIPLHVLVLMLTGRFSHRIYVAYCTVYCLGTILSMQISFVGFQPVLSSEHMAAFGVFG 275

  Fly   277 LLMAVATLRHLQSVLSRNEFRKLF-----IVGGLLVGVGVFVAVVVLTMLGVVAPWSGRFYSLWD 336
            |....|.:.:|:|.|:..:|..||     :||.:|:.||   |:::||  |.::||:||||||.|
Mouse   276 LCQIHAFVDYLRSKLNPQQFEVLFRSVISLVGFVLLTVG---ALLMLT--GKISPWTGRFYSLLD 335

  Fly   337 TGYAKIHIPIIASVSEHQPTTWFSFFFDLHILVCAFPVGVWYCIKQINDERVFVVLYAISAVYFA 401
            ..|||.:|||||||||||||||.|::|||.:||..||||::||...::|.|:|:::|.::::||:
Mouse   336 PSYAKNNIPIIASVSEHQPTTWSSYYFDLQLLVFMFPVGLYYCFSNLSDARIFIIMYGVTSMYFS 400

  Fly   402 GVMVRLMLTLTPVVCMLAGVAFSGLLDVFLQE-DSSKRMGTAISAATEVDEAEDSIEKKTLYDKA 465
            .|||||||.|.||:|:|:|:..|.:|..:::. |.|:.                        ||.
Mouse   401 AVMVRLMLVLAPVMCILSGIGVSQVLSTYMKNLDISRP------------------------DKK 441

  Fly   466 GKLKHRTKHDAQQDT--GVSSNLKSIVILAVLMLLMMFAVHCTWVTSNAYSSPSIVLAFHNSQDG 528
            .|        .|||:  .:.:.:.|.:||.:...|:.:..|.|||||.|||||||||:.... ||
Mouse   442 SK--------KQQDSTYPIKNEVASGMILVMAFFLITYTFHSTWVTSEAYSSPSIVLSARGG-DG 497

  Fly   529 SRNILDDFREAYYWLSQNTADDARVMSWWDYGYQIAGMANRTTLVDNNTWNNSHIALVGKAMSST 593
            ||.|.||||||||||..||.:||:|||||||||||..|||||.|||||||||:||:.||:||:||
Mouse   498 SRIIFDDFREAYYWLRHNTPEDAKVMSWWDYGYQITAMANRTILVDNNTWNNTHISRVGQAMAST 562

  Fly   594 EEKSYEIMTSLDVDYVLVIFGGVIGYSGDDINKFLWMVRIA----EGEHPKDIKESDYFTDRGEF 654
            |||:||||..|||.||||||||:.|||.||||||||||||.    .|.|   |||:||:|..|||
Mouse   563 EEKAYEIMRELDVSYVLVIFGGLTGYSSDDINKFLWMVRIGGSTETGRH---IKENDYYTPTGEF 624

  Fly   655 RVDAEGAPALLNCLMYKLSYYRFGELKLDYRGPSGYDRTRNAVIGNKDFDLTYLEEAYTTEHWLV 719
            |||.||:|.||||||||:.|||||::..:.:.|.|:||.|||.||||||:|..||||||||||||
Mouse   625 RVDREGSPVLLNCLMYKMCYYRFGQVYTEAKRPPGFDRVRNAEIGNKDFELDVLEEAYTTEHWLV 689

  Fly   720 RIYRVK 725
            |||:||
Mouse   690 RIYKVK 695

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Stt3B	NP_524494.1	STT3	18..514	CDD:396873	264/503 (52%)
Stt3a	NP_032434.3	STT3	17..484	CDD:396873	264/503 (52%)
		DXD motif 1. /evidence=ECO:0000250|UniProtKB:Q5HTX9	47..49		1/1 (100%)
		DXD motif 2. /evidence=ECO:0000250|UniProtKB:P39007	167..169		1/1 (100%)
		SVSE motif. /evidence=ECO:0000250|UniProtKB:Q5HTX9	348..351		2/2 (100%)
		WWDYG motif. /evidence=ECO:0000250|UniProtKB:P39007	525..529		3/3 (100%)
		Interacts with target acceptor peptide in protein substrate. /evidence=ECO:0000250|UniProtKB:B9KDD4	525..527		1/1 (100%)
		DK motif. /evidence=ECO:0000250|UniProtKB:P39007	592..599		6/6 (100%)