DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PQBP1 and pqbp-1.1

DIOPT Version :9

Sequence 1:	NP_651331.1	Gene:	PQBP1 / 43004	FlyBaseID:	FBgn0039270	Length:	231	Species:	Drosophila melanogaster
Sequence 2:	NP_499890.2	Gene:	pqbp-1.1 / 176847	WormBaseID:	WBGene00020647	Length:	280	Species:	Caenorhabditis elegans

Alignment Length:	228	Identity:	74/228 - (32%)
Similarity:	111/228 - (48%)	Gaps:	50/228 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSLPAALLQRLKKRGLVTKQSGAAPISEAIEEIIAENYDDDDKSGPYPYKEDTSPEPKRRSVEEK 65
            |.||.|||.||:|||:|.::          ||:|||||:               .||:::|.||
Worm     1 MPLPPALLARLQKRGIVKQE----------EEVIAENYE---------------KEPEKKSFEE- 39

  Fly    66 FWSHRIKERIGVNESYHGYKLCPNKYNIYHKCSLYCVNKF-NSSPLSQPSHRYLKRYKRLLRKYP 129
                        |.:  |...||||:|.||.|..:|.:.: :.:|..:...||::...|:|.|:|
Worm    40 ------------NSA--GAPGCPNKWNQYHVCLEFCYDHWGDGTPEYRLPERYVQNKNRMLAKFP 90

  Fly   130 LEAGWKDVYDKGCKAFYFYNSTTQTVSWLPPSHPKARITNSAAVFRRQLA-------NSNDEFNF 187
            |...|.:|||:|...:||:|.||..|.|..|.||:|.|::.|....|:.|       ::::|.|.
Worm    91 LPENWVEVYDEGLAKYYFWNKTTDEVCWYSPRHPRAIISDPAPRIAREHATVLFGDSHASEEDNA 155

  Fly   188 --DTNMVQPKSSNQNEPDEPDVFVPAKKQKSRD 218
              ..|....|:|.....|:......|:|:|.||
Worm   156 ARRRNFHNKKTSRGGNDDKQSRGNNAEKRKRRD 188

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PQBP1	NP_651331.1	WW	130..160	CDD:278809	13/29 (45%)
pqbp-1.1	NP_499890.2	WW	90..122	CDD:197736	14/31 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3427
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	106	1.000	Inparanoid score	I3510
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48631
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006017
OrthoInspector	1	1.000	-	-		oto20097
orthoMCL	1	0.900	-	-		OOG6_106865
Panther	1	1.100	-	-	LDO	PTHR21737
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R10618
SonicParanoid	1	1.000	-	-		X4933
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.900