Protein Alignment veli and LIN7C

DIOPT Version :9

• Sequence 1: NP_733076.2
• Gene: veli / 43003
• FlyBaseID: FBgn0039269
• Length: 246
• Species: Drosophila melanogaster
• Sequence 2: NP_060832.1
• Gene: LIN7C / 55327
• HGNCID: 17789
• Length: 197
• Species: Homo sapiens
• Alignment Length: 246
• Identity: 156/246 - (63%)
• Similarity: 172/246 - (69%)
• Gaps: 51/246 - (20%)

  Fly     1 MADNAEPLTLSRDVKRSIELLEKLQASGDFPTTKLAALQKVLNSDFMTSVREVYEHVYETVDIQG 65
            ||...||:.|.||:.|:||||||||.||:.|..||.|||:||.|:|..:||||||||||||||..
Human     1 MAALGEPVRLERDICRAIELLEKLQRSGEVPPQKLQALQRVLQSEFCNAVREVYEHVYETVDISS 65

  Fly    66 SHDVRASATAKATVAAFAASEGHAHPRVVELPKTEEGKTRPYELRIEGIPLYHKTNTLIVKVYRP 130
            |.:|||:||||||||||||||||:||||||||||||
Human    66 SPEVRANATAKATVAAFAASEGHSHPRVVELPKTEE----------------------------- 101

  Fly   131 RIYVSIIHLIWKALSIFNFCFSGLGFNVMGGKEQNSPIYISRIIPGGVADRHGGLKRGDQLLSVN 195
                                  |||||:|||||||||||||||||||:|||||||||||||||||
Human   102 ----------------------GLGFNIMGGKEQNSPIYISRIIPGGIADRHGGLKRGDQLLSVN 144

  Fly   196 GVSVEGENHEKAVELLKQAVGSVKLVVRYTPKVLEEMEMRFDKQRNTRRRQ 246
            |||||||:|||||||||.|.|.||||||||||||||||.||:|.|:.:|||
Human   145 GVSVEGEHHEKAVELLKAAQGKVKLVVRYTPKVLEEMESRFEKMRSAKRRQ 195

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
veli	NP_733076.2	L27	14..66	CDD:280918	35/51 (69%)
		PDZ_signaling	153..223	CDD:238492	63/69 (91%)
LIN7C	NP_060832.1	Kinase interacting site. /evidence=ECO:0000250	2..13		4/10 (40%)
		L27	14..66	CDD:397114	35/51 (69%)
		PDZ_signaling	91..172	CDD:238492	74/131 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165160208
Domainoid	1	1.000	134	1.000	Domainoid score	I5016
eggNOG	1	0.900	-	-		E1_KOG3550
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	285	1.000	Inparanoid score	I2859
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48622
OrthoDB	1	1.010	-	-		D1335138at2759
OrthoFinder	1	1.000	-	-		FOG0001780
OrthoInspector	1	1.000	-	-		otm41266
orthoMCL	1	0.900	-	-		OOG6_105974
Panther	1	1.100	-	-	LDO	PTHR14063
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2983
SonicParanoid	1	1.000	-	-		X1136
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800