DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment veli and lin7b

DIOPT Version :9

Sequence 1:	NP_733076.2	Gene:	veli / 43003	FlyBaseID:	FBgn0039269	Length:	246	Species:	Drosophila melanogaster
Sequence 2:	XP_002934676.1	Gene:	lin7b / 100491827	XenbaseID:	XB-GENE-5827098	Length:	207	Species:	Xenopus tropicalis

Alignment Length:	246	Identity:	155/246 - (63%)
Similarity:	170/246 - (69%)	Gaps:	51/246 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MADNAEPLTLSRDVKRSIELLEKLQASGDFPTTKLAALQKVLNSDFMTSVREVYEHVYETVDIQG 65
            ||...|||.|.|||.|:|||||:||.||:.|..||.|||:||.|.|.::||||||.:|:|:||.|
Frog     1 MAALPEPLGLERDVCRAIELLERLQRSGEVPPQKLQALQRVLQSKFCSAVREVYEQLYDTLDITG 65

  Fly    66 SHDVRASATAKATVAAFAASEGHAHPRVVELPKTEEGKTRPYELRIEGIPLYHKTNTLIVKVYRP 130
            |.::||.|||||||||||||||||||||||||||:|
Frog    66 SAEIRAHATAKATVAAFAASEGHAHPRVVELPKTDE----------------------------- 101

  Fly   131 RIYVSIIHLIWKALSIFNFCFSGLGFNVMGGKEQNSPIYISRIIPGGVADRHGGLKRGDQLLSVN 195
                                  |||||:|||||||||||||||||||||||||||||||||||||
Frog   102 ----------------------GLGFNIMGGKEQNSPIYISRIIPGGVADRHGGLKRGDQLLSVN 144

  Fly   196 GVSVEGENHEKAVELLKQAVGSVKLVVRYTPKVLEEMEMRFDKQRNTRRRQ 246
            |||||||.|||||||||.|.|:||||||||||||||||.||:|.|..||||
Frog   145 GVSVEGEQHEKAVELLKAAQGTVKLVVRYTPKVLEEMEARFEKMRTARRRQ 195

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
veli	NP_733076.2	L27	14..66	CDD:280918	31/51 (61%)
veli	NP_733076.2	PDZ_signaling	153..223	CDD:238492	64/69 (93%)
lin7b	XP_002934676.1	L27	14..66	CDD:367207	31/51 (61%)
lin7b	XP_002934676.1	PDZ_signaling	91..172	CDD:238492	74/131 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	134	1.000	Domainoid score	I4963
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H22648
Inparanoid	1	1.050	288	1.000	Inparanoid score	I2760
OMA	1	1.010	-	-		QHG48622
OrthoDB	1	1.010	-	-		D1335138at2759
OrthoFinder	1	1.000	-	-		FOG0001780
OrthoInspector	1	1.000	-	-		otm48473
Panther	1	1.100	-	-	O	PTHR14063
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1136
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.080