Protein Alignment stac and SYT12

DIOPT Version :10

• Sequence 1: NP_651329.4
• Gene: stac / 43002
• FlyBaseID: FBgn0266719
• Length: 1153
• Species: Drosophila melanogaster
• Sequence 2: XP_011543648.1
• Gene: SYT12 / 91683
• HGNCID: 18381
• Length: 456
• Species: Homo sapiens
• Alignment Length: 340
• Identity: 78/340 - (22%)
• Similarity: 123/340 - (36%)
• Gaps: 128/340 - (37%)

  Fly    57 SSLAPLEENGSGGEEDSDESPDGTLQLSQDSE----CTSI-DTFATESTLAS---SSDKDISTSV 113
            |.|.|||..|    .:.|.:|.|||:.||.::    .:|: :||..:.||..   |.:.|.::..
Human   143 SELGPLELMG----RELDLAPYGTLRKSQSADSLNSISSVSNTFGQDFTLGQVEVSMEYDTASHT 203

  Fly   114 LDSAPVMNVTDLY--EEILFEI------------------------------------------- 133
            |:.| ||...||.  ||..||.
Human   204 LNVA-VMQGKDLLEREEASFESCFMRVSLLPDEQIVGISRIQRNAYSIFFDEKFSIPLDPTALEE 267

  Fly   134 ----FNNIGCENNE-ECTNSLVE-----------------FVQDAFKIPNATHEEIYEAARLKEP 176
                |:..|.:.:| ..:..:||                 ::||..|..:|..|.:...:.|  |
Human   268 KSLRFSVFGIDEDERNVSTGVVELKLSVLDLPLQPFSGWLYLQDQNKAADAVGEILLSLSYL--P 330

  Fly   177 PNVRLNVEIIKAENLMSKDSNGLSDPFVTLYLESNG--SHRYNSSVKPATLNPIWEEH--FSLPI 237
            ...||.|.::||:||:..:....:||||.:||..:|  ..:..::||....||::.|.  ||:|
Human   331 TAERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDGRKMSKKKTAVKRDDPNPVFNEAMIFSVP- 394

  Fly   238 TENARDEVLIVEVWDFDAAETVKEKVNKILDVKGVKGLSKLMKEIAVTASSGKHDN---ELIGRA 299
                     .:.:.|.....||.|                       ::|.|:.||   .:||.:
Human   395 ---------AIVLQDLSLRVTVAE-----------------------SSSDGRGDNVGHVIIGPS 427

  Fly   300 AITLKSIPVSGLTVW 314
            |..:      |.|.|
Human   428 ASGM------GTTHW 436

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
stac	NP_651329.4	C2	152..317	CDD:472691	43/170 (25%)
		MUN	<637..1003	CDD:461870
		C2B_Munc13-like	990..1116	CDD:175976
SYT12	XP_011543648.1	C2	187..298	CDD:472691	19/111 (17%)
		C2B_Synaptotagmin-12	319..454	CDD:176051	39/159 (25%)