Protein Alignment stac and SYT5

DIOPT Version :10

• Sequence 1: NP_651329.4
• Gene: stac / 43002
• FlyBaseID: FBgn0266719
• Length: 1153
• Species: Drosophila melanogaster
• Sequence 2: NP_003171.2
• Gene: SYT5 / 6861
• HGNCID: 11513
• Length: 386
• Species: Homo sapiens
• Alignment Length: 293
• Identity: 72/293 - (24%)
• Similarity: 120/293 - (40%)
• Gaps: 47/293 - (16%)

  Fly   150 VEFVQDAFKIPNATHEEIYEAARLK-----EPPNVRLNVEIIKAENLMSKDSNGLSDPFVTLYLE 209
            ||.::.|...|.....:.:|..||:     :..:.:|.|.|::|..|.:.|..|.|||:|.:||.
Human    89 VEELEPAPSGPGQQVADKHELGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLL 153

  Fly   210 SNGSHRYNSSVKPATLNPIWEEHFS--LPITENARDEVLIVEVWDF------DAAETVKEKVNKI 266
            .:...||.:.|...||||.:.|.|:  :|..| ....||::.|:||      ||...|:..::.:
Human   154 PDKRRRYETKVHRQTLNPHFGETFAFKVPYVE-LGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSV 217

  Fly   267 LDVKGVKGLSKLMKEIAVTASSGKHDNELIGRAAITLKSIPVSG-LTVWYNLEKGSKGRSRGSL- 329
            ...:.|:...:|.       ::.:.:.|.:|....:|:.:|.:| |||.....|..|....|.|
Human   218 DLGRPVQAWRELQ-------AAPREEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLS 275

  Fly   330 ----LVNLALSAEKNKSVAVQEHKNLL----KLLLMYELETSQ---------VANYWWSGKFSPN 377
                .|:|....:|.:.......||.|    .....:|:...|         |.:|...||....
Human   276 DPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAI 340

  Fly   378 AELIRSQHAAQSGLTPFDCAL-------SQWHA 403
            ..:.....|..:||..:...|       :|||:
Human   341 GRVAVGAAAGGAGLRHWADMLANPRRPIAQWHS 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
stac	NP_651329.4	C2	152..317	CDD:472691	47/178 (26%)
		MUN	<637..1003	CDD:461870
		C2B_Munc13-like	990..1116	CDD:175976
SYT5	NP_003171.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..23
		Syt1_2_N	<21..76	CDD:409247
		C2A_Synaptotagmin-1-5-6-9-10	109..231	CDD:176031	36/129 (28%)
		C2	240..374	CDD:472691	30/134 (22%)