Protein Alignment stac and baiap3

DIOPT Version :10

• Sequence 1: NP_651329.4
• Gene: stac / 43002
• FlyBaseID: FBgn0266719
• Length: 1153
• Species: Drosophila melanogaster
• Sequence 2: XP_002938461.3
• Gene: baiap3 / 100492796
• XenbaseID: XB-GENE-956301
• Length: 1172
• Species: Xenopus tropicalis
• Alignment Length: 1258
• Identity: 317/1258 - (25%)
• Similarity: 574/1258 - (45%)
• Gaps: 235/1258 - (18%)

  Fly    11 FFKLQELKMNPPTEHEHQL----QDGDDGFFEKFGSLLRQKSQID-----EGVLKSSLAPLEENG 66
            |.:..|::.:..|:...::    ::|...||::..|:|:::..:.     ||||.:|:.|..||
 Frog    21 FRRRAEMESSNSTQETCKVPSADREGTGDFFDRMRSVLQKQENMQRYWRTEGVLNNSIPPPPEN- 84

  Fly    67 SGGEEDSDESPDGTLQLSQDSECTSIDTFATESTLASSSDKDISTSVLDSAPVMNVTDLYEEILF 131
             .||..                       ..|..|.|..:.::               ||||||:
 Frog    85 -VGEHK-----------------------VLEKLLLSKREIEM---------------LYEEILY 110

  Fly   132 EIFNNIGCENNEE--CTNSLVEFVQDAFKIPNATHEEIYEAARLKEPPNVRLNVEIIKAENLMSK 194
            .:....|..::|.  ....|..::|..|.:..:.|:.|.:..:..:.|...|.|.:::..||::|
 Frog   111 TLVYTAGIVSSEHIGSEEELFHYLQKVFGVSKSDHDPILQHVKESKAPVFALKVTVVQGRNLLAK 175

  Fly   195 DSNGLSDPFVTLYL---------ESNGSHRYN-------------------------SSVKPATL 225
            |.||.|||:..|.:         |.....:::                         :.||..||
 Frog   176 DPNGFSDPYCMLGIMIMQSSKETEEKKERKFSFRKKKDKIEKRSSIREVLPAKYIQVTEVKSNTL 240

  Fly   226 NPIWEEHFSLPITENARDEVLIVEVWDFDAAETVKEKVNKILDVKGVKGLSKLMKEI-------A 283
            ||:|.|:|...|.:...|: |.:::||.|...:|.|...|:.:|.|.||:.:..|:|       .
 Frog   241 NPVWNENFLFEIDDIFSDQ-LHLDIWDHDDDVSVAEACKKLNEVSGFKGMGRYFKQIVKSARANG 304

  Fly   284 VTASSGKHDNELIGRAAITLKSIPVSGLTVWYNLE-KGSKGRSRGS--LLVNL-------ALSAE 338
            .|.|:..:.::.:|...|::..|||.||..|:.|| :.|..|.:|.  |::.|       .||.:
 Frog   305 TTGSAEDNADDFLGCLNISINEIPVGGLDKWFKLEPRTSSSRVQGDCHLIIKLITNQRDTVLSKK 369

  Fly   339 KNKSVAVQEHKNLLKLLLMYELETSQVANYWWSGKFSPNAELIRSQHAAQSGLTPFDCALSQWHA 403
            .:.||.   |:.||..||.||.:.::|.::.|.|:.|.:|..|.|.|:.|:.|:....|:.:|.|
 Frog   370 ASGSVI---HEMLLNQLLQYEHKQTEVESWNWKGELSKHAFTILSHHSMQTDLSSLQQAVIKWQA 431

  Fly   404 YSTIHETHKLNFTLFNSILDVVV----PVITYMQNDSEDVKTFWDGVKRLLPSCFAVLRKLRSK- 463
            :|..|:...::::....:|..:.    |.:...:.:....::|    ......|..:|:|||..
 Frog   432 FSKHHQIQAMDYSFLLGLLKHIEEQWDPTMCQREQEQSLAESF----TLFTEYCLLLLKKLRDNF 492

  Fly   464 ---NTSDKNIIRALNEVLDILKKIKELEVPESVDIFPKSVYGWLHTNDTDETCNIDTAIEDAINT 525
               ||:   :|..|..:|..|.:|:.::....|..|    :..||..           |...|..
 Frog   493 PVLNTT---VINRLEFMLRCLSQIQNMQAFRMVCPF----HNELHLE-----------IAAIIKK 539

  Fly   526 GTREWLEHIVEGSR-QSKNTETDDEKLQYVIKLIQMVRSDLQRAMEYFDKIFYHKIQLNYSAVLY 589
            ||.||.|......| :.|||.   |:|:.:.:|...|..|::::...::|:|...::::|.::.|
 Frog   540 GTLEWYEKTHASLRPEEKNTV---EQLRCLARLTDAVHEDIEKSQNVYNKLFVSIVKVDYFSITY 601

  Fly   590 LFYDSKLAEICKSIIIEVCNNIKRLDVPDDQFEYLPNLENVNMGTTLFEVYLIL------KRYVQ 648
                .:|.::....:......:|..:....|..:.       :|..|:|:|:.|      :.|:.
 Frog   602 ----RQLEKLVADEVSAAMGALKGTEPESPQITHA-------IGEALYELYITLSELRKFRDYLP 655

  Fly   649 LGESLCSEPLELSNFYPWFERGVTHWLDISIIKALSRIQKAIDLDQLKAVDETVKYSSSAVDTLS 713
            |.:   ::.|.||.|:..|:..:..||.....|...|||:|::||:|:.||...|:||||||...
 Frog   656 LKD---NKSLALSGFHELFKVSIHTWLITIHEKTCERIQRAVELDKLEYVDSLSKHSSSAVDVTI 717

  Fly   714 IFYQIKIFWQQLDWPEVEGSYIFVAKIVNDLCRCCIFYAQQMSRRVENIFIADDNNKNFILSEEW 778
            .|.|||.||.||.||:...:::|:.::.:|:|:..|:|::.:.|:|:....|.....  :::|:.
 Frog   718 CFSQIKEFWAQLAWPDSAEAFVFLTQLSDDICKAAIYYSEAIRRKVDKSHQASVGQA--VITEQL 780

  Fly   779 CIAINNMDYIRQSLPSFIKELSIDDIIKRLGEYRTNLEAERCASTI-KTVIENALDTE------- 835
            ||.:||:::||:.:.:.:::|....:         .:..|....|. |..::.||:|:
 Frog   781 CIVLNNIEHIRKFMGNILRDLDWKPL---------EMAVELSPGTDGKPQVQKALNTQLQNIDID 836

  Fly   836 -----RNQIVELIEIVARKMAPPIRRYLAEGAEVLAKDSNSMDQ----LMMYLESSLATLYDTLN 891
                 :|.|..|.|    ||...|::|:...:  |:.||...|:    ||.||:..|..|.:||.
 Frog   837 MQREAKNMISHLTE----KMIGDIKKYIQHIS--LSPDSIQNDEAVSPLMKYLDDKLIILNETLV 895

  Fly   892 EINFQRILDGIWSELSIIMYDLIQSNLDKRRPPAFFQNLNNTLQTMMDCF-------KMGNLQTS 949
            :.|..|:||.:|..|...:.|.:.||  :.....|:.....||:.::|.|       .:..|:..
 Frog   896 KENLHRVLDALWWLLLKFIIDAVDSN--RGVSVEFYGRFYYTLEALVDFFHAEGQGLALETLRNG 958

  Fly   950 DIKILSSIQSRLRLYSLETSDLIHQYYLERLENQKSQESSPYGQLTITA--QLTDTGLLLNILNA 1012
            |.:.|   :..|||....||:||.:|||:..:.|:|.|.|.||:|::..  :.::..|.:.:|:|
 Frog   959 DYRFL---EEELRLNKCSTSELIEKYYLDNTKEQRSSEQSKYGRLSVKCYYESSEQKLYVEVLHA 1020

  Fly  1013 RNLLPMDSNGSVDSFVKASFMPTSRFNDVPTVKTNVHNKSCFPLYDQEFRINLSDHQRSEKNSLI 1077
            .:|:.:|:||..|.||.....|...|..|...:|.|..|:..|:||:.|..::|..|...|::.|
 Frog  1021 ADLIALDANGLSDPFVIIELCPHHIFPLVKCQRTQVKPKTLHPVYDELFYFSVSSEQCRRKSACI 1085

  Fly  1078 VFSIKDKD-----------------LFGMSSQYIAESYISFADLEATPPGEQIMMNLSRPEYTDS 1125
            :|::.|.|                 ::|::..:|.      ..::...|   .::.|:||:....
 Frog  1086 LFTVMDHDWLSTNDFAGEAVLPMNVIYGLNRPHIT------GGVKNVQP---TVLKLTRPKANVK 1141

  Fly  1126 ESLRALEYRLGDKQAKDFLKKLK 1148
            ..|:.|:.|: ||:|::|:|||:
 Frog  1142 SILKMLDGRM-DKEAQEFVKKLR 1163

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
stac	NP_651329.4	C2	152..317	CDD:472691	52/205 (25%)
		MUN	<637..1003	CDD:461870	115/397 (29%)
		C2B_Munc13-like	990..1116	CDD:175976	33/144 (23%)
baiap3	XP_002938461.3	C2A_Munc13-like	133..338	CDD:176058	52/205 (25%)
		C2	<233..>306	CDD:472691	24/73 (33%)
		MUN	<656..950	CDD:461870	91/315 (29%)
		C2B_Munc13-like	996..1117	CDD:175976	31/120 (26%)