DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31109 and set-16

DIOPT Version :9

Sequence 1:	NP_001262946.1	Gene:	CG31109 / 43001	FlyBaseID:	FBgn0051109	Length:	198	Species:	Drosophila melanogaster
Sequence 2:	NP_499819.3	Gene:	set-16 / 176802	WormBaseID:	WBGene00011729	Length:	2475	Species:	Caenorhabditis elegans

Alignment Length:	220	Identity:	46/220 - (20%)
Similarity:	71/220 - (32%)	Gaps:	47/220 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 KACISGFLCRLCSEMHRTVIHIYSDHGQRLCLVEKINGYLPITISPTDPLPKTICKSCLHRVEQH 70
            :.|.....|..|..|      |.:|  .|.|...:.:.:|....|....|...:|.||..|.:..
Worm    35 RQCDMSSSCGSCQRM------ITAD--SRQCTTCRKSYHLSCDSSDVSSLNNFVCISCRRRSQML 91

  Fly    71 YSLLMRLTRMREER------------KFKLIKYKAQRNPSISSVESEEDVINS--SSVHEFPNRN 121
            ...:|.....|..|            ....|..:.|..|..||....:|....  :.:.....:.
Worm    92 PDDVMLSASARPSRGQDAPLSPFSDPSVPQISLQMQPAPLPSSYPRSQDFNGDVYTQIAAMQQQR 156

  Fly   122 EEDQATRRSESTSTQAE------TGPQTQESQSPKSTKTAVSTPNSSESHD---------ASGAG 171
            ::.|..:..:..:|||:      .|..|.:|...       |:|...|:.|         ..|.|
Worm   157 QQQQQNQVQQMLATQAQLMDEISDGGGTNDSDRN-------SSPFYQEASDYDEDFVPASTRGRG 214

  Fly   172 PSNRDRKETGTGNSETGSTTREGTH 196
            .....:|:.|.|.| ||  ||..|:
Worm   215 RGGGAKKKPGRGGS-TG--TRRQTN 236

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31109	NP_001262946.1	zf-AD	13..76	CDD:214871	14/62 (23%)
set-16	NP_499819.3	PHD_SF	42..84	CDD:276966	11/49 (22%)
		PHD4_KMT2C_like	427..477	CDD:276987
		PHD5_KMT2C_like	479..524	CDD:276988
		PHD6_KMT2C_like	554..604	CDD:276989
		DUF1351	1060..>1163	CDD:284492
		ePHD2_KMT2C_like	1904..2008	CDD:277136
		FYRN	2055..2104	CDD:283589
		FYRC	2112..2199	CDD:197781
		SET	2333..2457	CDD:214614
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900