Protein Alignment MLLT3 and Mllt3

DIOPT Version :10

• Sequence 1: NP_004520.2
• Gene: MLLT3 / 4300
• HGNCID: 7136
• Length: 568
• Species: Homo sapiens
• Sequence 2: NP_081602.3
• Gene: Mllt3 / 70122
• MGIID: 1917372
• Length: 569
• Species: Mus musculus
• Alignment Length: 569
• Identity: 560/569 - (98%)
• Similarity: 564/569 - (99%)
• Gaps: 1/569 - (0%)

Human     1 MASSCAVQVKLELGHRAQVRKKPTVEGFTHDWMVFVRGPEHSNIQHFVEKVVFHLHESFPRPKRV 65
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse     1 MASSCAVQVKLELGHRAQVRKKPTVEGFTHDWMVFVRGPEHSNIQHFVEKVVFHLHESFPRPKRV 65

Human    66 CKDPPYKVEESGYAGFILPIEVYFKNKEEPRKVRFDYDLFLHLEGHPPVNHLRCEKLTFNNPTED 130
            ||||||||||||||||||||||||||||||:||||||||||||||||||||||||||||||||||
Mouse    66 CKDPPYKVEESGYAGFILPIEVYFKNKEEPKKVRFDYDLFLHLEGHPPVNHLRCEKLTFNNPTED 130

Human   131 FRRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSK 195
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   131 FRRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSK 195

Human   196 PHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMS 260
            |||||||||||||||||||||||||||||||||||:|||||||||||||||||||||||||||||
Mouse   196 PHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKDSSKKPKENKPLKEEKIVPKMAFKEPKPMS 260

Human   261 KEPKPDSNLLTITSG-QDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLILTCSADK 324
            ||||.||||||:||| |||||||||||.|||||||||||||||||||||||||||||||||||||
Mouse   261 KEPKADSNLLTVTSGQQDKKAPSKRPPASDSEELSAKKRKKSSSEALFKSFSSAPPLILTCSADK 325

Human   325 KQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDSDVEENISSKSDSEQPSPASSSSSSS 389
            ||||||||||||||||||||||||||.||||||||||||||||||:|||||||||||||||||||
Mouse   326 KQIKDKSHVKMGKVKIESETSEKKKSMLPPFDDIVDPNDSDVEENMSSKSDSEQPSPASSSSSSS 390

Human   390 SSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDNDSEMERPVNRGGSRSRRVSLSDGSDSE 454
            ||||||||||||||||||||||||||||||||.||||||||||||||||||||||||||||||||
Mouse   391 SSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEAEDNDNDSEMERPVNRGGSRSRRVSLSDGSDSE 455

Human   455 SSSASSPLHHEPPPPLLKTNNNQILEVKSPIKQSKSDKQIKNGECDKAYLDELVELHRRLMTLRE 519
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   456 SSSASSPLHHEPPPPLLKTNNNQILEVKSPIKQSKSDKQIKNGECDKAYLDELVELHRRLMTLRE 520

Human   520 RHILQQIVNLIEETGHFHITNTTFDFDLCSLDKTTVRKLQSYLETSGTS 568
            |||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   521 RHILQQIVNLIEETGHFHITNTTFDFDLCSLDKTTVRKLQSYLETSGTS 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MLLT3	NP_004520.2	YEATS_AF-9_like	9..137	CDD:341125	126/127 (99%)
		Histone H3K9cr binding. /evidence=ECO:0000269|PubMed:27105114, ECO:0000269|PubMed:30385749, ECO:0007744|PDB:5HJB, ECO:0007744|PDB:5HJD, ECO:0007744|PDB:6MIL, ECO:0007744|PDB:6MIM	78..80		1/1 (100%)
		Histone H3K9cr binding. /evidence=ECO:0000269|PubMed:27105114, ECO:0000269|PubMed:30385749, ECO:0007744|PDB:5HJB, ECO:0007744|PDB:5HJD, ECO:0007744|PDB:6MIL, ECO:0007744|PDB:6MIM	106..108		1/1 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	138..475		329/337 (98%)
		Nuclear localization signal. /evidence=ECO:0000255	295..300		4/4 (100%)
		AHD	503..563	CDD:436050	59/59 (100%)
Mllt3	NP_081602.3	YEATS_AF-9_like	9..137	CDD:341125	126/127 (99%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	138..476		329/337 (98%)
		Nuclear localization signal. /evidence=ECO:0000255	296..301		4/4 (100%)
		AHD	504..564	CDD:436050	59/59 (100%)