Protein Alignment MLLT3 and yaf9

DIOPT Version :10

• Sequence 1: NP_004520.2
• Gene: MLLT3 / 4300
• HGNCID: 7136
• Length: 568
• Species: Homo sapiens
• Sequence 2: NP_593730.1
• Gene: yaf9 / 2542278
• PomBaseID: SPAC17G8.07
• Length: 217
• Species: Schizosaccharomyces pombe
• Alignment Length: 157
• Identity: 46/157 - (29%)
• Similarity: 77/157 - (49%)
• Gaps: 22/157 - (14%)

Human     3 SSCAVQVKLELGHRA------QVRKKPTVEGFTHDWMVFVRGPEHSNIQHFVEKVVFHLHESFPR 61
            |.|.:...:.:|:.|      :..|.||  ..||.|.:||.|.:..:|..:|.||||.||:::..
pombe     8 SKCQISRPILVGNDAKPLTKEEKEKAPT--DHTHTWRIFVEGVDGEDISKWVRKVVFKLHDTYNN 70

Human    62 PKRVCKDPPYKVEESGYAGFILPIEVYFKNKEEPRKVRFDYDLFLHLEGHPPVNHLRC------- 119
            |.|..:.||::|.|:|:..|.:.:.::|..:...:.:.|.:.|.||..| |.:..::.
pombe    71 PTRTIESPPFEVIETGWGEFDIMVRIFFAPEAHEKALTFYHHLKLHPYG-PRMEEMKASGGLVES 134

Human   120 ---EKLTFNNPTEDFRRKLLKAG--GD 141
               |::.||.|.| :..|||...  ||
pombe   135 VQYEEIVFNEPFE-YTYKLLSQNPIGD 160

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MLLT3	NP_004520.2	YEATS_AF-9_like	9..137	CDD:341125	41/143 (29%)
		Histone H3K9cr binding. /evidence=ECO:0000269|PubMed:27105114, ECO:0000269|PubMed:30385749, ECO:0007744|PDB:5HJB, ECO:0007744|PDB:5HJD, ECO:0007744|PDB:6MIL, ECO:0007744|PDB:6MIM	78..80		0/1 (0%)
		Histone H3K9cr binding. /evidence=ECO:0000269|PubMed:27105114, ECO:0000269|PubMed:30385749, ECO:0007744|PDB:5HJB, ECO:0007744|PDB:5HJD, ECO:0007744|PDB:6MIL, ECO:0007744|PDB:6MIM	106..108		1/1 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	138..475		2/6 (33%)
		Nuclear localization signal. /evidence=ECO:0000255	295..300
		AHD	503..563	CDD:436050
yaf9	NP_593730.1	TFG3	1..217	CDD:227366	46/157 (29%)