Protein Alignment CG11790 and Pdia5

DIOPT Version :10

• Sequence 1: NP_651326.1
• Gene: CG11790 / 42999
• FlyBaseID: FBgn0039265
• Length: 302
• Species: Drosophila melanogaster
• Sequence 2: NP_082571.1
• Gene: Pdia5 / 72599
• MGIID: 1919849
• Length: 517
• Species: Mus musculus
• Alignment Length: 254
• Identity: 47/254 - (18%)
• Similarity: 96/254 - (37%)
• Gaps: 55/254 - (21%)

  Fly    20 QDLRRVDDTELIQLLTGSSNVVVLFNKNNCQRC----VEYENMVTKIRAQLEETLSAI-VVQSVD 79
            :|.||:...|...||       ::|....|..|    ..::...|::|..:  .|:.: |..|..
Mouse   158 KDFRRLLKREEKPLL-------MMFYAPWCSMCKRIMPHFQKAATQVRGHI--VLAGMNVYPSEF 213

  Fly    80 SNLVSIYDPSKEPALVFFRRG---IPILYHGEINDDEILDFFNDNLEP--------------AVK 127
            .|:...|:....|.:.:|.:|   .|...:|...:| |:::..:.|.|              :|.
Mouse   214 ENIKEEYNVRGYPTICYFEKGRFLFPYENYGSTAED-IVEWLKNPLPPQPQVPETPWADEGGSVY 277

  Fly   128 ELSDDNFEHLTQASSGATTGDWFIFFSSAECTVCQRLYAVWESVGGKLKRKLNIARMNSLESGIS 192
            .|:|::|:...:..|..     .:.|.:..|..|:::...:||..       .:...::..||:.
Mouse   278 HLTDEDFDQFVKEHSSV-----LVMFHAPWCGHCKKMKPEFESAA-------EVLHGDAESSGVL 330

  Fly   193 TATRLGVLEA----------PAFIFLRQGKMYKYSAKQYSPEAFVQFAEKGYTQSHPQP 241
            .|....|.||          |...:.:.|:.....|.: :.:.|:::.:.......|:|
Mouse   331 AAVDATVNEALAGRFHISAFPTLKYFKNGEQQAVPALR-TKKKFIEWMQNPEAPPPPEP 388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11790	NP_651326.1	PTZ00102	27..>174	CDD:240266	32/168 (19%)
		PTZ00443	125..302	CDD:185622	22/127 (17%)
Pdia5	NP_082571.1	PDI_b_PDIR_N	26..137	CDD:239365
		PDI_a_PDIR	150..254	CDD:239295	23/105 (22%)
		PDI_a_PDIR	275..377	CDD:239295	20/114 (18%)
		PDI_a_PDIR	396..499	CDD:239295
		Prevents secretion from ER. /evidence=ECO:0000255|PROSITE-ProRule:PRU10138	514..517