Protein Alignment CG11790 and Erp27

DIOPT Version :10

• Sequence 1: NP_651326.1
• Gene: CG11790 / 42999
• FlyBaseID: FBgn0039265
• Length: 302
• Species: Drosophila melanogaster
• Sequence 2: NP_081259.1
• Gene: Erp27 / 69187
• MGIID: 1916437
• Length: 272
• Species: Mus musculus
• Alignment Length: 135
• Identity: 27/135 - (20%)
• Similarity: 54/135 - (40%)
• Gaps: 38/135 - (28%)

  Fly    20 QDLRRVDDTELIQLLTGSSNVVVLFNKNNCQRCVEYENMVTKIRAQLEETLSAIVVQSVDSNLVS 84
            :|:..:|..:|.:.:          :.||.....||..|   |.|.|..|:       |.::|:.
Mouse   122 EDIENLDAAKLSRFI----------HVNNLHWVTEYSPM---IAAGLFNTM-------VQTHLLL 166

  Fly    85 IY---DPSKEPALVFFRRGIPILYHGEI----------NDDEILDFF--NDNLEP--AVKELSDD 132
            :.   .|..|.::..:|.... |:.|:|          .:.:::.:|  .::..|  |:.|..||
Mouse   167 MMKKTSPEYEESMRRYREAAK-LFQGQILFVLVDSGKRENGKVMSYFKLKESQLPALAIYESVDD 230

  Fly   133 NFEHL 137
            .::.|
Mouse   231 KWDTL 235

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11790	NP_651326.1	PTZ00102	27..>174	CDD:240266	25/128 (20%)
		PTZ00443	125..302	CDD:185622	5/13 (38%)
Erp27	NP_081259.1	Thioredoxin_6	64..250	CDD:463999	27/135 (20%)
		PDIA3-binding site. /evidence=ECO:0000250|UniProtKB:Q96DN0	230..233		1/2 (50%)
		Prevents secretion from ER. /evidence=ECO:0000250|UniProtKB:Q96DN0	269..272