DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11790 and prtp

DIOPT Version :9

Sequence 1:	NP_651326.1	Gene:	CG11790 / 42999	FlyBaseID:	FBgn0039265	Length:	302	Species:	Drosophila melanogaster
Sequence 2:	NP_001188583.1	Gene:	prtp / 32124	FlyBaseID:	FBgn0030329	Length:	416	Species:	Drosophila melanogaster

Alignment Length:	255	Identity:	57/255 - (22%)
Similarity:	99/255 - (38%)	Gaps:	46/255 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 IVSVVIIALSLG-------CAVGQDLRRVD-------DTELIQLLTGSSNVVVLFNKNNCQRCVE 54
            |:||.:..|.|.       .:..:|..:.|       |.|.........||.|.|....|..|
  Fly     6 ILSVAVCGLLLSPLLPITRASQEEDTGKQDKQFTVELDPETFDTAIAGGNVFVKFFAPWCGHC-- 68

  Fly    55 YENMVTKIRAQLEETLSA----IVVQSVD----SNLVSIYDPSKEPALVFFRRG--IPILYHGEI 109
              ..:..:..||.|.::.    :::..||    ..|.:.:..:..|.|..|:.|  ..:.:.|..
  Fly    69 --KRIQPLWEQLAEIMNVDNPKVIIAKVDCTKHQGLCATHQVTGYPTLRLFKLGEEESVKFKGTR 131

  Fly   110 NDDEILDFFNDNLE-PAVKELSDDNFEHLTQASSG-------------ATTGDWFIFFSSAECTV 160
            :...|.||.|..|. ||..:|.:...|.:...:.|             .:||:.|:.|.:..|:.
  Fly   132 DLPAITDFINKELSAPAEADLGEVKREQVENLNIGKVVDLTEDTFAKHVSTGNHFVKFFAPWCSH 196

  Fly   161 CQRLYAVWESVGGKLKRK--LNIARMNSLESGISTATRLGVLEAPAFIFLRQG-KMYKYS 217
            ||||...||.:..:|.::  :.|::::..:.. |......|...|..:::..| |:.|||
  Fly   197 CQRLAPTWEDLAKELIKEPTVTISKIDCTQFR-SICQDFEVKGYPTLLWIEDGKKIEKYS 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11790	NP_651326.1	PDI_a_family	127..230	CDD:239259	24/107 (22%)
prtp	NP_001188583.1	PDI_a_ERp46	38..140	CDD:239303	21/105 (20%)
		ER_PDI_fam	39..409	CDD:273457	50/222 (23%)
		PDI_a_ERp46	167..267	CDD:239303	21/90 (23%)
		PDI_a_ERp46	303..407	CDD:239303
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0191
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810