DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11790 and Erp27

DIOPT Version :9

Sequence 1:	NP_651326.1	Gene:	CG11790 / 42999	FlyBaseID:	FBgn0039265	Length:	302	Species:	Drosophila melanogaster
Sequence 2:	NP_001100095.1	Gene:	Erp27 / 297698	RGDID:	1565381	Length:	272	Species:	Rattus norvegicus

Alignment Length:	135	Identity:	32/135 - (23%)
Similarity:	57/135 - (42%)	Gaps:	35/135 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 DLRRVDDTELIQLLTGSSNVVVLFNKNNCQRCVEYENMVTKIRAQLEETLSAIVVQSVDSNLVSI 85
            |...:||.:..:|    |..:.|   ||.....||..|   |.|.|..|:       |.::|:.|
  Rat   120 DAEDIDDLDAAKL----SRFIHL---NNLHWVTEYSPM---IGAGLFNTM-------VQTHLLLI 167

  Fly    86 YD---PSKEPALVFFRRGIPILYHGEI----------NDDEILDFF--NDNLEP--AVKELSDDN 133
            .:   |..|.:|..:::... |:.|:|          .:.:::.:|  .::..|  |:.|..||.
  Rat   168 MNKASPEYEESLRSYQKAAK-LFQGQILFVLVDSGKRENGKVIAYFRLKESQLPALAIYESVDDK 231

  Fly   134 FEHLT 138
            ::.||
  Rat   232 WDALT 236

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11790	NP_651326.1	PDI_a_family	127..230	CDD:239259	5/12 (42%)
Erp27	NP_001100095.1	PDI_b_family	43..139	CDD:239279	6/25 (24%)
		Thioredoxin_6	64..250	CDD:290560	32/135 (24%)
		PDI_b'_family	156..253	CDD:239280	18/89 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0191
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900