Protein Alignment CG11790 and P4hb

DIOPT Version :10

• Sequence 1: NP_651326.1
• Gene: CG11790 / 42999
• FlyBaseID: FBgn0039265
• Length: 302
• Species: Drosophila melanogaster
• Sequence 2: NP_037130.2
• Gene: P4hb / 25506
• RGDID: 3244
• Length: 509
• Species: Rattus norvegicus
• Alignment Length: 347
• Identity: 77/347 - (22%)
• Similarity: 129/347 - (37%)
• Gaps: 73/347 - (21%)

  Fly     6 SVVIIALSLGCAVGQDLRRVDDTELI-------QLLTGSSNVVVLFNKNNCQRC----VEYENMV 59
            :::.:||:....||.|....:|..|:       :.|...:.::|.|....|..|    .||....
  Rat     5 ALLCLALAWAARVGADALEEEDNVLVLKKSNFAEALAAHNYLLVEFYAPWCGHCKALAPEYAKAA 69

  Fly    60 TKIRAQLEETLSAIVVQSVDSNLVSIYDPSKEPALVFFRRG---IPILYHGEINDDEILDFFNDN 121
            .|::|:..|...|.|..:.:|:|...|.....|.:.||:.|   .|..|......|:|:::....
  Rat    70 AKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFKNGDTASPKEYTAGREADDIVNWLKKR 134

  Fly   122 LEPAVKELSDD-NFEHLTQASSGATTGDWFIFFSSAECTVCQRLYAVWESV-------------- 171
            ..||...|||. ..|.|..:|.....|    ||..|.....::.....|:|
  Rat   135 TGPAATTLSDTAAAESLVDSSEVTVIG----FFKDAGSDSAKQFLLAAEAVDDIPFGITSNSDVF 195

  Fly   172 --------GGKLKRKLNIARMNSLESGISTATRLGVLEAPAFIFLRQGKMYKYSAKQYSPEAFVQ 228
                    |..|.:|.:..| |:.|..|   |:..:|:   ||...|..:.....:|.:|:.|
  Rat   196 SKYQLDKDGVVLFKKFDEGR-NNFEGEI---TKEKLLD---FIKHNQLPLVIEFTEQTAPKIF-- 251

  Fly   229 FAEKGYTQSHPQPVPAIPSAVNEFLGPLQSY-FAAENITSLATLSIFALV---------ALLFVG 283
               .|..::|  .:..:|.:|:::.|.|.:: .|||......   :|..:         .|.|.|
  Rat   252 ---GGEIKTH--ILLFLPKSVSDYDGKLSNFKKAAEGFKGKI---LFIFIDSDHTDNQRILEFFG 308

  Fly   284 KK-----VAKIFSSEPAKTKNK 300
            .|     ..::.:.|...||.|
  Rat   309 LKKEECPAVRLITLEEEMTKYK 330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11790	NP_651326.1	PTZ00102	27..>174	CDD:240266	40/183 (22%)
		PTZ00443	125..302	CDD:185622	46/214 (21%)
P4hb	NP_037130.2	ER_PDI_fam	26..476	CDD:273457	72/326 (22%)
		Prevents secretion from ER	506..509