Protein Alignment CG11790 and PDIA6

DIOPT Version :9

• Sequence 1: NP_651326.1
• Gene: CG11790 / 42999
• FlyBaseID: FBgn0039265
• Length: 302
• Species: Drosophila melanogaster
• Sequence 2: NP_001269633.1
• Gene: PDIA6 / 10130
• HGNCID: 30168
• Length: 492
• Species: Homo sapiens
• Alignment Length: 290
• Identity: 55/290 - (18%)
• Similarity: 98/290 - (33%)
• Gaps: 96/290 - (33%)

  Fly    33 LLTGSSNVVVL----FNK------------------NNCQRCV-EYENMVTKIRAQLEETLSAIV 74
            |.:.|.:|:.|    ||:                  .:|||.. |::...|.::       ..:.
Human    72 LYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAATALK-------DVVK 129

  Fly    75 VQSVDS----NLVSIYDPSKEPALVFF--RRGIPILYHGEINDDEILDFFNDNLEPAVK------ 127
            |.:||:    :|...|.....|.:..|  .:..|..|.|....:.|:|.....|...||
Human   130 VGAVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGR 194

  Fly   128 ---------------------ELSDDNFEHLTQASSGATTGDWFIFFSSAECTVCQRLYAVWESV 171
                                 ||:||:|:.....|...    |.:.|.:..|..|:.|...|.:.
Human   195 SGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDV----WMVEFYAPWCGHCKNLEPEWAAA 255

  Fly   172 GGKLKR----KLNIARMNSLESGISTATRLGVLEAPAFIFLRQGKMYKYSAKQYSPEAFVQFAEK 232
            ..::|.    |:.:|.:::..:.: .|:|.|:...|.....::|:         ||..:    :.
Human   256 ASEVKEQTKGKVKLAAVDATVNQV-LASRYGIRGFPTIKIFQKGE---------SPVDY----DG 306

  Fly   233 GYTQ-----------SHPQPVPAIPSAVNE 251
            |.|:           |...|.|.:...:||
Human   307 GRTRSDIVSRALDLFSDNAPPPELLEIINE 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11790	NP_651326.1	PDI_a_family	127..230	CDD:239259	23/133 (17%)
PDIA6	NP_001269633.1	PDI_a_P5	78..180	CDD:239299	21/108 (19%)
		PDI_a_P5	213..318	CDD:239299	24/122 (20%)
		P5_C	327..456	CDD:239281	3/10 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0191
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900