DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bai and tmed-10

DIOPT Version :9

Sequence 1:	NP_651323.3	Gene:	bai / 42996	FlyBaseID:	FBgn0045866	Length:	206	Species:	Drosophila melanogaster
Sequence 2:	NP_505879.1	Gene:	tmed-10 / 179567	WormBaseID:	WBGene00009829	Length:	204	Species:	Caenorhabditis elegans

Alignment Length:	207	Identity:	109/207 - (52%)
Similarity:	145/207 - (70%)	Gaps:	15/207 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 FIVCLLMACAWSSHAVMFKLSPNTQKCLKEDIQANQLVMGEFEVSDVPGQIIDYI----ARDTKG 66
            |:..:::|     |::.|.:.|..:|||||:|..|.:|.||:|.|    |.|.|.    ..||:|
Worm     7 FLSAIVLA-----HSLRFYVPPKEKKCLKEEIHKNVVVTGEYEFS----QGIQYTGSIHVTDTRG 62

  Fly    67 HILSQKEHIT--KGKFSFMSEVYDTYEICFISKVPAHQRGVIQEVSLLTKKGVETKSYEGIGEAS 129
            |.|.::|:..  ||||:|.::.||.:|||..:..||...|..:||||:.|.|||.|:|:.|.:|.
Worm    63 HTLYKRENFADLKGKFAFTADEYDIFEICIENHPPAGHPGEKREVSLILKHGVEAKNYDDIAKAE 127

  Fly   130 KLKPLEVDLKRLEDLSDSIVRDFVLMRKREEEMRDTNEKTNSRVLFFSIFSMCCLLGLATWQVLY 194
            |||||||:|:||||::|||.:||..||:||||||:|||.||||||:.|||||.||||||.||||:
Worm   128 KLKPLEVELRRLEDMADSITKDFAFMRQREEEMRNTNESTNSRVLYLSIFSMLCLLGLAIWQVLF 192

  Fly   195 LRRYFKAKKLIE 206
            ||.|||:||||:
Worm   193 LRNYFKSKKLID 204

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bai	NP_651323.3	EMP24_GP25L	20..200	CDD:279450	100/185 (54%)
tmed-10	NP_505879.1	EMP24_GP25L	16..198	CDD:366467	100/185 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159404
Domainoid	1	1.000	195	1.000	Domainoid score	I1846
eggNOG	1	0.900	-	-		E1_KOG1691
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4972
Inparanoid	1	1.050	207	1.000	Inparanoid score	I2411
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53581
OrthoDB	1	1.010	-	-		D1370889at2759
OrthoFinder	1	1.000	-	-		FOG0001316
OrthoInspector	1	1.000	-	-		oto20584
orthoMCL	1	0.900	-	-		OOG6_101611
Panther	1	1.100	-	-	LDO	PTHR22811
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1531
SonicParanoid	1	1.000	-	-		X178
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	15	14.840