DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ythdf and ECT8

DIOPT Version :9

Sequence 1:	NP_001262943.1	Gene:	Ythdf / 42995	FlyBaseID:	FBgn0039261	Length:	700	Species:	Drosophila melanogaster
Sequence 2:	NP_565205.1	Gene:	ECT8 / 844267	AraportID:	AT1G79270	Length:	528	Species:	Arabidopsis thaliana

Alignment Length:	422	Identity:	151/422 - (35%)
Similarity:	203/422 - (48%)	Gaps:	90/422 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   181 MVPGKHNLDVNVWDLPNNKPPPVPSPP--SPI---------DLGYSDLSSD------------FS 222
            ::||..:.|.:...:|.| |..|.|..  ||:         ..||:|:||.            :.
plant   110 LMPGFQSYDASQTYMPIN-PVGVSSQALHSPMYAAQGYYQNQFGYADVSSPTYLWDPVGDRYVYG 173

  Fly   223 ISSNTAPPLGARAEKVHKDTENFLKYEHKGLGNNNNFSRAKVSPTGPVRRNLGPQQPVHHAAPRP 287
            ::|.| |||          .:|.....|   .:||.:|::|.|.||            |....||
plant   174 VASYT-PPL----------KQNISSSSH---NHNNYYSKSKNSFTG------------HGMGDRP 212

  Fly   288 ATNAGPFGPPNARRHDGGPHPSRNSERSGNYSSFRGSEFESASKFEYRDENQ---SRPVEATSAT 349
            .|      |..|.::...|.|..|.|:  ...::.....:..|....|||.:   :|..|..::.
plant   213 KT------PRKASQNSYAPPPLLNQEK--GRIAYPMDPVKKKSGALNRDETEKAKARTKENGTSM 269

  Fly   350 EELPVDSQLV---------LD-ELKDKNN----------YNPKVLDLKKAGSARFFVIKSYSEDD 394
            .:|......:         || |..:::|          ||......|.. .|.|||||||||||
plant   270 NDLANGQDHITNGECESCSLDAEGNERSNGVGSVIRRDQYNLPSFQTKYE-EAIFFVIKSYSEDD 333

  Fly   395 IHRSIKYEIWCSTDHGNKRLDDAFKERHEEGGN------IMLFFSVNGSGHFCGMAQMMTPVDYN 453
            ||:||||.:|.||.:|||:||.|::|..::..:      :.||||||.||.|||:|:|:..|||.
plant   334 IHKSIKYNVWSSTLNGNKKLDSAYQESQKKAADKSGKCPVFLFFSVNASGQFCGVAEMIGRVDYE 398

  Fly   454 STSSVWSQDKWRGKFKVKWIYVKDVPNGTLRHIRLENNENKSVTNSRDTQEVPNDKGIEVLQILH 518
            .:...|.||||.|.|.|||..:|||||..||||.|||||||.||||||||||...:|.|||.|..
plant   399 KSMEFWQQDKWTGYFPVKWHIIKDVPNPQLRHIILENNENKPVTNSRDTQEVRLPQGNEVLNIFK 463

  Fly   519 SYNHSTSIFDDFFHYEKKQEEEVSSKR--PPM 548
            :|...|||.|||..||.:::..|..|.  ||:
plant   464 NYAAKTSILDDFDFYENREKVMVQKKLRFPPV 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ythdf	NP_001262943.1	YTH	382..518	CDD:309322	85/141 (60%)
ECT8	NP_565205.1	YTH	321..463	CDD:398013	85/141 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	176	1.000	Domainoid score	I1083
eggNOG	1	0.900	-	-		E1_KOG1901
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000639
OrthoInspector	1	1.000	-	-		otm2739
orthoMCL	1	0.900	-	-		OOG6_102335
Panther	1	1.100	-	-	O	PTHR12357
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X383
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	10	9.770