DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ythdf and ECT4

DIOPT Version :9

Sequence 1:	NP_001262943.1	Gene:	Ythdf / 42995	FlyBaseID:	FBgn0039261	Length:	700	Species:	Drosophila melanogaster
Sequence 2:	NP_001321789.1	Gene:	ECT4 / 841997	AraportID:	AT1G55500	Length:	605	Species:	Arabidopsis thaliana

Alignment Length:	448	Identity:	146/448 - (32%)
Similarity:	203/448 - (45%)	Gaps:	89/448 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   152 ASQPAKL-TSRAASTTSNSKKKGPGMPPPPMVPGKHNLDVNVWDLPNNKPPPVPSPPSP------ 209
            ||..:|| |::||::.|....||                      .|...|..|...|.
plant   165 ASTQSKLSTNKAANSASAGIPKG----------------------MNGSAPVKPLNQSALYGNSA 207

  Fly   210 ----IDLGYSDLSSDFSISSNTAPPLGARAEKVHKDTENFLKYEHKGLGNNNNFSRAKVSPTGPV 270
                :..||.|....:.         |........|..||...:....|:....|.:|.:...|.
plant   208 LGGGLAAGYQDPRYSYD---------GFYTPVSWHDGSNFSDVQRSVSGSGVASSYSKANNNVPA 263

  Fly   271 RRNLGPQQPVHHAAP-RPATNAG--------------PFGPPNARRHDG-----GPHPSRNSER- 314
            .||.......|:.:. :||:..|              .:|...:....|     ..:.||.:||
plant   264 TRNQNSSSNSHYTSMYQPASMTGYAAQGYYDRVSPNKSYGQYGSTVRSGMGYGSSGYGSRTNERG 328

  Fly   315 ----SGNYSSFRG---SEFESASKFEYRDE-NQSRPVEATSATEELPVDSQLVLDELKDKNNYNP 371
                ...|.| ||   |.|......:..:| |:....:.|.||||  |.|:.|..:..|::|...
plant   329 WLNTDNKYRS-RGRGNSYFYGNENIDGLNELNRGPRAKGTKATEE--VSSEEVKKQTFDESNTEE 390

  Fly   372 KVL----DLKKAG---------SARFFVIKSYSEDDIHRSIKYEIWCSTDHGNKRLDDAFKERHE 423
            .|.    |.::..         .|:||:||||||||:|:||||.:|.||.:|||:||.|::|..:
plant   391 TVTCVLPDREECNRDDFPVEYKDAKFFIIKSYSEDDVHKSIKYNVWASTPNGNKKLDAAYQEAQQ 455

  Fly   424 E--GGNIMLFFSVNGSGHFCGMAQMMTPVDYNSTSSVWSQDKWRGKFKVKWIYVKDVPNGTLRHI 486
            :  |..:.||||||.||.|.|:|:|..|||:|.....|.||||.|.|.:||..:|||||..|:||
plant   456 KSSGCPVFLFFSVNASGQFIGLAEMKGPVDFNKNIEYWQQDKWTGSFPLKWHILKDVPNSLLKHI 520

  Fly   487 RLENNENKSVTNSRDTQEVPNDKGIEVLQILHSYNHSTSIFDDFFHYEKKQEEEVSSK 544
            .||.||||.||||||||||..::|::|::|...:|..|.|.|||..||.:|:..:..|
plant   521 TLEYNENKPVTNSRDTQEVKLEQGLKVVKIFKEHNSKTCILDDFSFYEARQKTILEKK 578

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ythdf	NP_001262943.1	YTH	382..518	CDD:309322	79/137 (58%)
ECT4	NP_001321789.1	IFT43	361..>407	CDD:317678	12/47 (26%)
ECT4	NP_001321789.1	YTH	414..552	CDD:309322	79/137 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	176	1.000	Domainoid score	I1083
eggNOG	1	0.900	-	-		E1_KOG1901
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000639
OrthoInspector	1	1.000	-	-		otm2739
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12357
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X383
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	9	8.870