DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ythdf and ECT3

DIOPT Version :9

Sequence 1:	NP_001262943.1	Gene:	Ythdf / 42995	FlyBaseID:	FBgn0039261	Length:	700	Species:	Drosophila melanogaster
Sequence 2:	NP_851236.1	Gene:	ECT3 / 836223	AraportID:	AT5G61020	Length:	495	Species:	Arabidopsis thaliana

Alignment Length:	516	Identity:	154/516 - (29%)
Similarity:	216/516 - (41%)	Gaps:	138/516 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 ANANHDSYRRHGHSIPNNTRRDEHQVNPWNSRKPAAQSFRNENDQPSTKLD----NRTSDEAQNQ 137
            ||.:|.|...|..||                 .|..::...:::   |||.    ...:|...|.
plant     2 ANPDHVSDVLHNLSI-----------------DPTTKALAPDSE---TKLQGAYGGNGNDFLLND 46

  Fly   138 EVVAAPKKTTWASIASQPAKLTSRAASTT---SNSKKKG------------------PGMPPPPM 181
            |:|.|.|       ..:|:.|:.....|.   ||.||.|                  .|..||..
plant    47 ELVEATK-------IGKPSLLSKDGGVTKDKGSNLKKLGYQSAAYNAKGSYGKGAYAYGYYPPAY 104

  Fly   182 VPGKHNLDVNVWDLPNNKPPPVPSPPSPIDLGYSDLSSDFSISSNTAPPLGARAEKVHKDTENFL 246
            ...:|                          ||:                |:.|.........:|
plant   105 QYPRH--------------------------GYT----------------GSYASGKTNLQYQYL 127

  Fly   247 KYEHKGLGNNNNFS------RAKVSPTGPVRRNLG------------PQQPVHHAAPRPATNAGP 293
            ..:.:..||..::.      .:.....||.....|            |.....:...:|......
plant   128 TQQGRSAGNGQSYGGYMDNIYSNYGMCGPYTNGYGYGSYGYDSWKYMPNWYAVNNTYKPRNGYHG 192

  Fly   294 FGPPNARRHDGGPHPSRNSERSGNYSSFRGSEFESASKFEYRDENQSRPVEATSATEELPVDSQL 358
            :|..|..    |.:......|:..::|..||:..:.|..|.|          .:.||:|..|..|
plant   193 YGKENIE----GLNEMNRGPRAKGFNSQDGSKVMAVSLKEQR----------VTETEKLSEDVSL 243

  Fly   359 VLDELKDKNNYNPKVLDLKKA-GSARFFVIKSYSEDDIHRSIKYEIWCSTDHGNKRLDDAFKE-- 420
            :     |..:||.  :|..:. ..|:|:|||||||||||:||||.:|.||.:|||:||.::.|
plant   244 L-----DPKDYNK--IDFPETYTEAKFYVIKSYSEDDIHKSIKYSVWSSTPNGNKKLDASYNEAK 301

  Fly   421 RHEEGGNIMLFFSVNGSGHFCGMAQMMTPVDYNSTSSVWSQDKWRGKFKVKWIYVKDVPNGTLRH 485
            :..:|..:.|.||||.||.|.|:|:|:.|||:|.|...|.||||.|.|.|||.:|||:||.:|||
plant   302 QKSDGCPVFLLFSVNTSGQFVGLAEMVGPVDFNKTVEYWQQDKWIGCFPVKWHFVKDIPNSSLRH 366

  Fly   486 IRLENNENKSVTNSRDTQEVPNDKGIEVLQILHSYNHSTSIFDDFFHYEKKQE--EEVSSK 544
            |.|||||||.||||||||||..::||:|::|...:...|.|.|||..||.:|:  :|..||
plant   367 ITLENNENKPVTNSRDTQEVKLEQGIKVIKIFKDHASKTCILDDFEFYENRQKIIQERKSK 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ythdf	NP_001262943.1	YTH	382..518	CDD:309322	83/137 (61%)
ECT3	NP_851236.1	YTH	261..399	CDD:398013	83/137 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	176	1.000	Domainoid score	I1083
eggNOG	1	0.900	-	-		E1_KOG1901
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000639
OrthoInspector	1	1.000	-	-		otm2739
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12357
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X383
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.870